Assessment of Structural Intolerance and Durability
General Structure Information 2k2d RCHY1 solution nmr structure of c-terminal domain of human pirh2. northeast structural genomics consortium (nesg) target ht2c -1.0Å AUTH Y.SHENG,R.C.LAISTER,A.LEMAK,B.WU,E.TAI,S.DUAN,AUTH 2 J.LUKIN,M.SUNNERHAGEN,S.SRISAILAM,M.KARRA,AUTH 3 S.BENCHIMOL,C.H.ARROWSMITHTITL MOLECULAR BASIS OF PIRH2-MEDIATED P53TITL 2 UBIQUITYLATION.REF NAT.STRUCT.MOL.BIOL. V. 15 1334 2008REFN ISSN 1545-9993PMID 19043414DOI 10.1038/NSMB.1521 Variant Set Distributions Mapped Variants
General Structure Information 2k2c RCHY1 solution nmr structure of n-terminal domain of human pirh2. northeast structural genomics consortium (nesg) target ht2a -1.0Å AUTH Y.SHENG,R.C.LAISTER,A.LEMAK,B.WU,E.TAI,S.DUAN,AUTH 2 J.LUKIN,M.SUNNERHAGEN,S.SRISAILAM,M.KARRA,AUTH 3 S.BENCHIMOL,C.H.ARROWSMITHTITL MOLECULAR BASIS OF PIRH2-MEDIATED P53TITL 2 UBIQUITYLATION.REF NAT.STRUCT.MOL.BIOL. V. 15 1334 2008REFN ISSN 1545-9993PMID 19043414DOI 10.1038/NSMB.1521 Variant Set Distributions Mapped Variants
General Structure Information 3oln UHRF2 crystal structure of the sra domain of e3 ubiquitin-protein ligase uhrf2 2.3Å AUTH J.R.WALKER,S.XUE,G.V.AVVAKUMOV,C.BOUNTRA,J.WEIGELT,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,A.BOCHKAREV,S.DHE-PAGANON,AUTH 3 STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL THE SET AND RING ASSOCIATED (SRA) DOMAIN OF HUMANTITL 2 UBIQUITIN-LIKE CONTAINING PHD AND RING FINGER DOMAINS 2TITL 3 (UHRF2)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3c5r BARD1 crystal structure of the bard1 ankyrin repeat domain and its functional consequences 2.0Å AUTH D.FOX,I.LE TRONG,P.RAJAGOPAL,P.S.BRZOVIC,R.E.STENKAMP,AUTH 2 R.E.KLEVITTITL CRYSTAL STRUCTURE OF THE BARD1 ANKYRIN REPEAT DOMAIN AND ITSTITL 2 FUNCTIONAL CONSEQUENCES.REF J.BIOL.CHEM. V. 283 21179 2008REFN ISSN 0021-9258PMID 18480049DOI 10.1074/JBC.M802333200 Variant Set Distributions Mapped Variants
General Structure Information 3ihw AGAP3 crystal structure of the ras-like domain of centg3 1.92Å AUTH L.NEDYALKOVA,W.TEMPEL,Y.TONG,Y.LI,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF THE RAS-LIKE DOMAIN OF CENTG3REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2kje CREBBP nmr structure of cbp taz2 and adenoviral e1a complex -1.0Å AUTH J.C.FERREON,M.A.MARTINEZ-YAMOUT,H.J.DYSON,AUTH 2 P.E.WRIGHTTITL STRUCTURAL BASIS FOR SUBVERSION OF CELLULAR CONTROLTITL 2 MECHANISMS BY THE ADENOVIRAL E1A ONCOPROTEIN.REF PROC.NATL.ACAD.SCI.USA V. 106 13260 2009REFN ISSN 0027-8424PMID 19651603DOI 10.1073/PNAS.0906770106 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 3f1i STAM human escrt-0 core complex 2.3Å AUTH X.REN,D.P.KLOER,Y.C.KIM,R.GHIRLANDO,L.F.SAIDI,G.HUMMER,AUTH 2 J.H.HURLEYTITL HYBRID STRUCTURAL MODEL OF THE COMPLETE HUMAN ESCRT-0TITL 2 COMPLEX.REF STRUCTURE V. 17 406 2009REFN ISSN 0969-2126PMID 19278655DOI 10.1016/J.STR.2009.01.012 Variant Set Distributions Mapped Variants
General Structure Information 3ddt TRIM63 crystal structure of the b2 box from murf1 in dimeric state 1.9Å AUTH M.MROSEK,S.MEIER,Z.UCURUM-FOTIADIS,E.VON CASTELMUR,AUTH 2 E.HEDBOM,A.LUSTIG,S.GRZESIEK,D.LABEIT,S.LABEIT,AUTH 3 O.MAYANSTITL STRUCTURAL ANALYSIS OF B-BOX 2 FROM MURF1:TITL 2 IDENTIFICATION OF A NOVEL SELF-ASSOCIATION PATTERNTITL 3 IN A RING-LIKE FOLDREF BIOCHEMISTRY V. 47 10722 2008REFN ISSN 0006-2960PMID 18795805DOI 10.1021/BI800733Z Variant Set Distributions […]
General Structure Information 2r02 PDCD6IP crystal structure of alix/aip1 in complex with the hiv-1 ypltsl late domain 2.6Å AUTH Q.ZHAI,R.D.FISHER,H.Y.CHUNG,D.G.MYSZKA,AUTH 2 W.I.SUNDQUIST,C.P.HILLTITL STRUCTURAL AND FUNCTIONAL STUDIES OF ALIXTITL 2 INTERACTIONS WITH YPX(N)L LATE DOMAINS OF HIV-1TITL 3 AND EIAV.REF NAT.STRUCT.MOL.BIOL. V. 15 43 2008REFN ISSN 1545-9993PMID 18066081DOI 10.1038/NSMB1319 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 2rc4 KAT6A crystal structure of the hat domain of the human moz protein 3.0Å AUTH M.A.HOLBERT,T.SIKORSKI,J.CARTEN,D.SNOWFLACK,S.HODAWADEKAR,AUTH 2 R.MARMORSTEINTITL THE HUMAN MONOCYTIC LEUKEMIA ZINC FINGER HISTONETITL 2 ACETYLTRANSFERASE DOMAIN CONTAINS DNA-BINDING ACTIVITYTITL 3 IMPLICATED IN CHROMATIN TARGETING.REF J.BIOL.CHEM. V. 282 36603 2007REFN ISSN 0021-9258PMID 17925393DOI 10.1074/JBC.M705812200 Variant Set Distributions Ripley’s K Analysis Plots […]