Assessment of Structural Intolerance and Durability
General Structure Information 2kxq SMURF2 solution structure of smurf2 ww2 and ww3 bound to smad7 py motif containing peptide -1.0Å AUTH P.A.CHONG,H.LIN,J.L.WRANA,J.D.FORMAN-KAYTITL COUPLING OF TANDEM SMAD UBIQUITINATION REGULATORY FACTORTITL 2 (SMURF) WW DOMAINS MODULATES TARGET SPECIFICITY.REF PROC.NATL.ACAD.SCI.USA V. 107 18404 2010REFN ISSN 0027-8424PMID 20937913DOI 10.1073/PNAS.1003023107 Variant Set Distributions Mapped Variants
General Structure Information 2yse MAGI1 solution structure of the second ww domain from the human membrane-associated guanylate kinase, ww and pdz domain- containing protein 1. magi-1 -1.0Å AUTH S.OHNISHI,M.SATO,S.KOSHIBA,T.HARADA,S.WATANABE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND WW DOMAIN FROMTITL 2 THE HUMAN MEMBRANE-ASSOCIATED GUANYLATE KINASE, WWTITL 3 AND PDZ DOMAIN-CONTAINING PROTEIN 1. MAGI-1REF TO BE […]
General Structure Information 3le4 DGCR8 crystal structure of the dgcr8 dimerization domain 1.7Å AUTH R.SENTURIA,M.FALLER,S.YIN,J.A.LOO,D.CASCIO,M.R.SAWAYA,AUTH 2 D.HWANG,R.T.CLUBB,F.GUOTITL STRUCTURE OF THE DIMERIZATION DOMAIN OF DIGEORGE CRITICALTITL 2 REGION 8REF PROTEIN SCI. V. 19 1354 2010REFN ISSN 0961-8368PMID 20506313DOI 10.1002/PRO.414 Variant Set Distributions Mapped Variants
General Structure Information 3l4h HECW1 helical box domain and second ww domain of the human e3 ubiquitin- protein ligase hecw1 1.8Å AUTH J.R.WALKER,L.QIU,Y.LI,J.WEIGELT,C.BOUNTRA,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,A.BOCHKAREV,S.DHE-PAGANONTITL THE TANDEM HELICAL BOX AND SECOND WW DOMAINS OF HUMAN HECW1REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2q5a PIN1 human pin1 bound to l-peptide 1.5Å AUTH Y.ZHANG,S.DAUM,D.WILDEMANN,X.Z.ZHOU,M.A.VERDECIA,M.E.BOWMAN,AUTH 2 C.LUCKE,T.HUNTER,K.P.LU,G.FISCHER,J.P.NOELTITL STRUCTURAL BASIS FOR HIGH-AFFINITY PEPTIDE INHIBITION OFTITL 2 HUMAN PIN1.REF ACS CHEM.BIOL. V. 2 320 2007REFN ISSN 1554-8929PMID 17518432DOI 10.1021/CB7000044 Variant Set Distributions Mapped Variants
General Structure Information 2m3o NEDD4 structure and dynamics of a human nedd4 ww domain-enac complex -1.0Å AUTH R.BOBBY,K.MEDINI,P.NEUDECKER,T.V.LEE,M.A.BRIMBLE,AUTH 2 F.J.MCDONALD,J.S.LOTT,A.J.DINGLEYTITL STRUCTURE AND DYNAMICS OF HUMAN NEDD4-1 WW3 IN COMPLEX WITHTITL 2 THE ALPHA ENAC PY MOTIF.REF BIOCHIM.BIOPHYS.ACTA V.1834 1632 2013REFN ISSN 0006-3002PMID 23665454DOI 10.1016/J.BBAPAP.2013.04.031 Variant Set Distributions Mapped Variants