Assessment of Structural Intolerance and Durability
General Structure Information 1wry SH3BGRL solution structure of the sh3 domain-binding glutamic acid- rich-like protein -1.0Å AUTH K.INOUE,K.MIYAMOTO,T.NAGASHIMA,F.HAYASHI,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SH3 DOMAIN-BINDINGTITL 2 GLUTAMIC ACID-RICH-LIKE PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2q53 GGCT ensemble refinement of the crystal structure of uncharacterized protein loc79017 from homo sapiens 2.01Å AUTH E.BAE,C.A.BINGMAN,D.J.ACETI,G.N.PHILLIPS JR.TITL CRYSTAL STRUCTURE OF HOMO SAPIENS PROTEIN LOC79017.REF PROTEINS V. 70 588 2008REFN ISSN 0887-3585PMID 17932939DOI 10.1002/PROT.21719 Variant Set Distributions Mapped Variants
General Structure Information 2zfh CUTA crystal structure of putative cuta1 from homo sapiens at 2.05a resolution 2.05Å AUTH B.BAGAUTDINOV,Y.MATSUURA,S.BAGAUTDINOVA,N.KUNISHIMA,K.YUTANITITL STRUCTURE OF PUTATIVE CUTA1 FROM HOMO SAPIENS DETERMINED ATTITL 2 2.05 A RESOLUTION.REF ACTA CRYSTALLOGR.,SECT.F V. 64 351 2008REFN ESSN 1744-3091PMID 18453701DOI 10.1107/S1744309108009846 Variant Set Distributions Mapped Variants
General Structure Information 1wx6 NCK2 solution structure of the sh3 domain of the human cytoplasmic protein nck2 -1.0Å AUTH S.OHNISHI,T.KIGAWA,T.TOMIZAWA,S.KOSHIBA,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SH3 DOMAIN OF THE HUMANTITL 2 CYTOPLASMIC PROTEIN NCK2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1z3k NCK2 structural insight into the binding diversity between the tyr-phosphorylated human ephrinbs and nck2 sh2 domain -1.0Å AUTH X.RAN,J.SONGTITL STRUCTURAL INSIGHT INTO THE BINDING DIVERSITYTITL 2 BETWEEN THE TYR-PHOSPHORYLATED HUMAN EPHRINBS ANDTITL 3 NCK2 SH2 DOMAIN.REF J.BIOL.CHEM. V. 280 19205 2005REFN ISSN 0021-9258PMID 15764601DOI 10.1074/JBC.M500330200 Variant Set Distributions Mapped Variants
General Structure Information 1jbi COCH nmr structure of the lccl domain -1.0Å AUTH E.LIEPINSH,M.TREXLER,A.KAIKKONEN,J.WEIGELT,AUTH 2 L.BANYAI,L.PATTHY,G.OTTINGTITL NMR STRUCTURE OF THE LCCL DOMAIN AND IMPLICATIONSTITL 2 FOR DFNA9 DEAFNESS DISORDER.REF EMBO J. V. 20 5347 2001REFN ISSN 0261-4189PMID 11574466DOI 10.1093/EMBOJ/20.19.5347 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2fbe RFPL4A crystal structure of the pryspry-domain 2.52Å AUTH C.GRUETTER,C.BRIAND,G.CAPITANI,P.R.MITTL,S.PAPIN,AUTH 2 J.TSCHOPP,M.G.GRUETTERTITL STRUCTURE OF THE PRYSPRY-DOMAIN: IMPLICATIONS FORTITL 2 AUTOINFLAMMATORY DISEASESREF FEBS LETT. V. 580 99 2006REFN ISSN 0014-5793PMID 16364311DOI 10.1016/J.FEBSLET.2005.11.076 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3al5 TYW5 crystal structure of human tyw5 2.5Å AUTH M.KATO,Y.ARAISO,A.NOMA,A.NAGAO,T.SUZUKI,R.ISHITANI,O.NUREKITITL CRYSTAL STRUCTURE OF A NOVEL JMJC-DOMAIN-CONTAINING PROTEIN,TITL 2 TYW5, INVOLVED IN TRNA MODIFICATION.REF NUCLEIC ACIDS RES. V. 39 1576 2011REFN ISSN 0305-1048PMID 20972222DOI 10.1093/NAR/GKQ919 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants