Assessment of Structural Intolerance and Durability
General Structure Information 3db5 PRDM4 crystal structure of methyltransferase domain of human pr domain- containing protein 4 2.15Å AUTH H.ZENG,M.F.AMAYA,P.LOPPNAU,A.BOCHKAREV,J.MIN,A.N.PLOTNIKOV,AUTH 2 H.WUTITL THE CRYSTAL STRUCTURE OF METHYLTRANSFERASE DOMAIN OF HUMANTITL 2 PR DOMAIN-CONTAINING PROTEIN 4.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3u5n TRIM33 crystal structure of the complex of trim33 phd-bromo and h3(1-20) k9me3k14ac histone peptide 1.95Å AUTH Q.XI,Z.WANG,A.I.ZAROMYTIDOU,X.H.ZHANG,L.F.CHOW-TSANG,AUTH 2 J.X.LIU,H.KIM,A.BARLAS,K.MANOVA-TODOROVA,V.KAARTINEN,AUTH 3 L.STUDER,W.MARK,D.J.PATEL,J.MASSAGUETITL A POISED CHROMATIN PLATFORM FOR TGF-BETA ACCESS TO MASTERTITL 2 REGULATORSREF CELL(CAMBRIDGE,MASS.) V. 147 1511 2011REFN ISSN 0092-8674PMID 22196728DOI 10.1016/J.CELL.2011.11.032 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 4c0d CNOT2 structure of the not module of the human ccr4-not complex (cnot1-cnot2-cnot3) 3.2Å AUTH A.BOLAND,Y.CHEN,T.RAISCH,S.JONAS,D.KUZUOGLU-OZTURK,AUTH 2 L.WOHLBOLD,O.WEICHENRIEDER,E.IZAURRALDETITL STRUCTURE AND ASSEMBLY OF THE NOT MODULE OF THE HUMANTITL 2 CCR4-NOT COMPLEXREF NAT.STRUCT.MOL.BIOL. V. 20 1289 2013REFN ISSN 1545-9993PMID 24121232DOI 10.1038/NSMB.2681 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 2csf SATB2 solution structure of the second cut domain of human satb2 -1.0Å AUTH K.INOUE,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND CUT DOMAIN OFTITL 2 HUMAN SATB2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2kt0 NANOG solution structure of human stem cell transcription factor nanog homeodomain fragment -1.0Å AUTH S.C.SAHU,J.L.MARKLEYTITL SOLUTION STRUCTURE OF HUMAN STEM CELL TRANSCRIPTION FACTORTITL 2 NANOGREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2yul SOX17 solution structure of the hmg box of human transcription factor sox-17 -1.0Å AUTH H.ABE,N.TOCHIO,K.MIYAMOTO,S.KOSHIBA,M.INOUE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE HMG BOX OF HUMANTITL 2 TRANSCRIPTION FACTOR SOX-17REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2epp PATZ1 solution structure of the first c2h2 type zinc finger domain of zinc finger protein 278 -1.0Å AUTH W.TANABE,S.SUZUKI,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST C2H2 TYPE ZINCTITL 2 FINGER DOMAIN OF ZINC FINGER PROTEIN 278REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4hfg RPRD1B cid of human rprd1b 2.0Å AUTH Z.NI,C.XU,W.TEMPEL,M.EL BAKKOURI,P.LOPPNAU,X.GUO,C.BOUNTRA,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,J.MIN,J.F.GREENBLATTTITL CID OF HUMAN RPRD1BREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4fla RPRD1B crystal structure of human rprd1b, carboxy-terminal domain 2.2Å AUTH Z.NI,C.XU,X.GUO,G.O.HUNTER,O.V.KUZNETSOVA,W.TEMPEL,E.MARCON,AUTH 2 G.ZHONG,H.GUO,W.H.KUO,J.LI,P.YOUNG,J.B.OLSEN,C.WAN,AUTH 3 P.LOPPNAU,M.EL BAKKOURI,G.A.SENISTERRA,H.HE,H.HUANG,AUTH 4 S.S.SIDHU,A.EMILI,S.MURPHY,A.L.MOSLEY,C.H.ARROWSMITH,J.MIN,AUTH 5 J.F.GREENBLATTTITL RPRD1A AND RPRD1B ARE HUMAN RNA POLYMERASE II C-TERMINALTITL 2 DOMAIN SCAFFOLDS FOR SER5 DEPHOSPHORYLATION.REF NAT.STRUCT.MOL.BIOL. V. 21 686 2014REFN ISSN 1545-9993PMID 24997600DOI 10.1038/NSMB.2853 Variant Set Distributions Mapped Variants
General Structure Information 4a9z TP63 crystal structure of human p63 tetramerization domain 2.29Å AUTH J.R.C.MUNIZ,D.COUTANDIN,E.SALAH,A.CHAIKUAD,M.VOLLMAR,AUTH 2 J.WEIGELT,C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,V.DOTSCH,AUTH 3 F.VON DELFT,S.KNAPPTITL CRYSTAL STRUCTURE OF HUMAN P63 TETRAMERIZATION DOMAINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants