General Structure Information 1z29 SULT1A2 crystal structures of sult1a2 and sult1a1*3: implications in the bioactivation of n-hydroxy-2-acetylamino fluorine (oh-aaf) 2.4Å AUTH J.LU,H.LI,J.ZHANG,M.LI,M.Y.LIU,X.AN,M.C.LIU,W.CHANGTITL CRYSTAL STRUCTURES OF SULT1A2 AND SULT1A1 *3: INSIGHTS INTOTITL 2 THE SUBSTRATE INHIBITION AND THE ROLE OF TYR149 IN SULT1A2.REF BIOCHEM.BIOPHYS.RES.COMMUN. V. 396 429 2010REFN ISSN 0006-291XPMID 20417180DOI 10.1016/J.BBRC.2010.04.109 Variant Set Distributions Ripley’s […]
General Structure Information 4n3b HCFC1 crystal structure of human o-glcnac transferase bound to a peptide from hcf-1 pro-repeat2(1-26)e10q and udp-5sglcnac 2.17Å AUTH M.B.LAZARUS,J.JIANG,V.KAPURIA,T.BHUIYAN,J.JANETZKO,AUTH 2 W.F.ZANDBERG,D.J.VOCADLO,W.HERR,S.WALKERTITL HCF-1 IS CLEAVED IN THE ACTIVE SITE OF O-GLCNAC TRANSFERASE.REF SCIENCE V. 342 1235 2013REFN ISSN 0036-8075PMID 24311690DOI 10.1126/SCIENCE.1243990 Variant Set Distributions Mapped Variants
General Structure Information 3caq AKR1D1 crystal structure of 5beta-reductase (akr1d1) in complex with nadph 2.2Å AUTH F.FAUCHER,L.CANTIN,V.LUU-THE,F.LABRIE,R.BRETONTITL CRYSTAL STRUCTURES OF HUMAN DELTA4-3-KETOSTEROIDTITL 2 5BETA-REDUCTASE (AKR1D1) REVEAL THE PRESENCE OF ANTITL 3 ALTERNATIVE BINDING SITE RESPONSIBLE FOR SUBSTRATETITL 4 INHIBITION (DAGGER) (,) (DOUBLE DAGGER).REF BIOCHEMISTRY V. 47 13537 2008REFN ISSN 0006-2960PMID 19075558DOI 10.1021/BI801276H Variant Set Distributions […]
General Structure Information 1ls6 SULT1A1 human sult1a1 complexed with pap and p-nitrophenol 1.9Å AUTH N.U.GAMAGE,R.G.DUGGLEBY,A.C.BARNETT,M.TRESILLIAN,AUTH 2 C.F.LATHAM,N.E.LIYOU,M.E.MCMANUS,J.L.MARTINTITL STRUCTURE OF A HUMAN CARCINOGEN-CONVERTING ENZYME,TITL 2 SULT1A1. STRUCTURAL AND KINETIC IMPLICATIONS OFTITL 3 SUBSTRATE INHIBITION.REF J.BIOL.CHEM. V. 278 7655 2003REFN ISSN 0021-9258PMID 12471039DOI 10.1074/JBC.M207246200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 1s5o CRAT structural and mutational characterization of l-carnitine binding to human carnitine acetyltransferase 1.8Å AUTH L.GOVINDASAMY,T.KUKAR,W.LIAN,B.PEDERSEN,Y.GU,AUTH 2 M.AGBANDJE-MCKENNA,S.JIN,R.MCKENNA,D.WUTITL STRUCTURAL AND MUTATIONAL CHARACTERIZATION OFTITL 2 L-CARNITINE BINDING TO HUMAN CARNITINETITL 3 ACETYLTRANSFERASE.REF J.STRUCT.BIOL. V. 146 416 2004REFN ISSN 1047-8477PMID 15099582DOI 10.1016/J.JSB.2004.01.011 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants