Assessment of Structural Intolerance and Durability
General Structure Information 2dax RWDD2B solution structure of the rwd domain of human protein c21orf6 -1.0Å AUTH M.YONEYAMA,T.KIGAWA,K.SAITO,N.TOCHIO,S.KOSHIBA,AUTH 2 M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RWD DOMAIN OF HUMANTITL 2 PROTEIN C21ORF6REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2o52 RAB4B crystal structure of human rab4b in complex with gdp 2.2Å AUTH H.ZHU,W.TEMPEL,J.WANG,Y.SHEN,R.LANDRY,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,M.SUNDSTROM,J.WEIGELT,AUTH 3 A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF HUMAN RAB4B IN COMPLEX WITHTITL 2 GDPREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2yuv MYBPC1 solution structure of 2nd immunoglobulin domain of slow type myosin-binding protein c -1.0Å AUTH T.N.NIRAULA,N.TOCHIO,S.KOSHIBA,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF 2ND IMMUNOGLOBULIN DOMAIN OFTITL 2 SLOW TYPE MYOSIN-BINDING PROTEIN CREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3edv SPTBN1 crystal structure of repeats 14-16 of beta2-spectrin 1.95Å AUTH L.DAVIS,K.ABDI,M.MACHIUS,C.BRAUTIGAM,D.R.TOMCHICK,AUTH 2 V.BENNETT,P.MICHAELYTITL LOCALIZATION AND STRUCTURE OF THE ANKYRIN-BINDINGTITL 2 SITE ON BETA2-SPECTRINREF J.BIOL.CHEM. V. 284 6982 2009REFN ISSN 0021-9258PMID 19098307DOI 10.1074/JBC.M809245200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2cte HDLBP solution structure of the 1st kh type i domain from human vigilin -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 1ST KH TYPE I DOMAINTITL 2 FROM HUMAN VIGILINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2ihd RGS8 crystal structure of human regulator of g-protein signaling 8, rgs8 1.7Å AUTH M.SOUNDARARAJAN,F.S.WILLARD,A.J.KIMPLE,A.P.TURNBULL,AUTH 2 L.J.BALL,G.A.SCHOCH,C.GILEADI,O.Y.FEDOROV,E.F.DOWLER,AUTH 3 V.A.HIGMAN,S.Q.HUTSELL,M.SUNDSTROM,D.A.DOYLE,D.P.SIDEROVSKITITL STRUCTURAL DIVERSITY IN THE RGS DOMAIN AND ITS INTERACTIONTITL 2 WITH HETEROTRIMERIC G PROTEIN ALPHA-SUBUNITS.REF PROC.NATL.ACAD.SCI.USA V. 105 6457 2008REFN ISSN 0027-8424PMID 18434541DOI 10.1073/PNAS.0801508105 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 1×50 LGALS4 solution structure of the c-terminal gal-bind lectin domain from human galectin-4 -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,K.SAITO,S.KOSHIBA,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE C-TERMINAL GAL-BINDTITL 2 LECTIN DOMAIN FROM HUMAN GALECTIN-4REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1x2p PRMT2 solution structure of the sh3 domain of the protein arginine n-methyltransferase 2 -1.0Å AUTH E.CHIKAYAMA,T.KIGAWA,K.SAITO,S.KOSHIBA,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SH3 DOMAIN OF THETITL 2 PROTEIN ARGININE N-METHYLTRANSFERASE 2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1×44 MYBPC1 solution structure of the third ig-like domain of myosin- dinding protein c, slow-type -1.0Å AUTH X.-R.QIN,C.KUROSAKI,F.HAYASHI,M.YOSHIDA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE THIRD IG-LIKE DOMAIN OFTITL 2 MYOSIN-DINDING PROTEIN C, SLOW-TYPEREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2z5d UBE2H human ubiquitin-conjugating enzyme e2 h 2.1Å AUTH Y.SHENG,J.H.HONG,R.DOHERTY,T.SRIKUMAR,J.SHLOUSH,AUTH 2 G.V.AVVAKUMOV,J.R.WALKER,S.XUE,D.NECULAI,J.W.WAN,S.K.KIM,AUTH 3 C.H.ARROWSMITH,B.RAUGHT,S.DHE-PAGANONTITL A HUMAN UBIQUITIN CONJUGATING ENZYME (E2)-HECT E3 LIGASETITL 2 STRUCTURE-FUNCTION SCREEN.REF MOL.CELL PROTEOMICS V. 11 329 2012REFN ISSN 1535-9476PMID 22496338DOI 10.1074/MCP.O111.013706 Variant Set Distributions Mapped Variants