Assessment of Structural Intolerance and Durability
General Structure Information 2p57 ARFGAP2 gap domain of znf289, an id1-regulated zinc finger protein 1.8Å AUTH Y.TONG,S DIMOV,L.SHEN,H.ZHU,W.TEMPEL,R.LANDRY,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,M.SUNDSTROM,J.WEIGELT,AUTH 3 A.BOCHKAREV,H.PARKTITL GAP DOMAIN OF ZNF289, AN ID1-REGULATED ZINC FINGERTITL 2 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2da4 HDX solution structure of the homeobox domain of the hypothetical protein, dkfzp686k21156 -1.0Å AUTH S.OHNISHI,T.KIGAWA,K.SAITO,S.KOSHIBA,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE HOMEOBOX DOMAIN OF THETITL 2 HYPOTHETICAL PROTEIN, DKFZP686K21156REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3qik PREX1 crystal structure of the first pdz domain of prex1 2.29Å AUTH L.SHEN,Y.TONG,W.TEMPEL,Y.LI,C.H.ARROWSMITH,A.M.EDWARDS,AUTH 2 C.BOUNTRA,J.WEIGELT,H.PARKTITL CRYSTAL STRUCTURE OF THE FIRST PDZ DOMAIN OF PREX1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ecc HOMEZ solution structure of the second homeobox domain of human homeodomain leucine zipper-encoding gene (homez) -1.0Å AUTH S.OHNISHI,Y.O.KAMATARI,N.TOCHIO,N.KOBAYASHI,AUTH 2 S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND HOMEOBOX DOMAINTITL 2 OF HUMAN HOMEODOMAIN LEUCINE ZIPPER-ENCODING GENETITL 3 (HOMEZ)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3k2j PBRM1 crystal structure of the 3rd bromodomain of human poly-bromodomain containing protein 1 (pb1) 2.2Å AUTH P.FILIPPAKOPOULOS,S.PICAUD,T.KEATES,A.CHAIKUAD,A.C.W.PIKE,AUTH 2 T.KROJER,R.SETHI,F.VON DELFT,C.H.ARROWSMITH,A.EDWARDS,AUTH 3 J.WEIGELT,C.BOUNTRA,S.KNAPPTITL CRYSTAL STRUCTURE OF THE 3RD BROMODOMAIN OF HUMANTITL 2 POLY-BROMODOMAIN CONTAINING PROTEIN 1 (PB1)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2jxx NFATC2IP nmr solution structure of ubiquitin-like domain of nfatc2ip. northeast structural genomics consortium target hr5627 -1.0Å AUTH R.S.DOHERTY,S.DHE-PAGANON,C.FARES,A.LEMAK,C.BUTLER,AUTH 2 S.SRISAILAM,M.KARRA,A.YEE,J.WEIGELT,A.M.EDWARDS,AUTH 3 C.H.ARROWSMITHTITL SOLUTION STRUCTURE OF UBIQUITIN-LIKE DOMAIN OFTITL 2 NFATC2IP.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2cry KIRREL3 solution structure of the fifth ig-like domain of human kin of irre like 3 -1.0Å AUTH C.KUROSAKI,F.HAYASHI,M.YOSHIDA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIFTH IG-LIKE DOMAIN OFTITL 2 HUMAN KIN OF IRRE LIKE 3REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3syx SPRED1 crystal structure of the wh1 domain from human sprouty-related, evh1 domain-containing protein. northeast structural genomics consortium target hr5538b. 2.45Å AUTH S.VOROBIEV,M.SU,J.SEETHARAMAN,S.SAHDEV,R.XIAO,C.CICCOSANTI,AUTH 2 R.SHASTRY,J.K.EVERETT,R.NAIR,T.B.ACTON,B.ROST,AUTH 3 G.T.MONTELIONE,L.TONG,J.F.HUNTTITL CRYSTAL STRUCTURE OF THE WH1 DOMAIN FROM HUMANTITL 2 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2yqr KIAA0907 solution structure of the kh domain in kiaa0907 protein -1.0Å AUTH S.KADIRVEL,F.HE,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,AUTH 2 T.TARADA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE KH DOMAIN IN KIAA0907TITL 2 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3n9u CPSF7 crystal structure of the complex between the 25 kda subunit and the 59 kda subunit (rrm domain) of human cleavage factor im 1.92Å AUTH L.TRESAUGUES,M.WELIN,C.H.ARROWSMITH,H.BERGLUND,C.BOUNTRA,AUTH 2 R.COLLINS,A.M.EDWARDS,S.FLODIN,A.FLORES,S.GRASLUND,AUTH 3 M.HAMMARSTROM,I.JOHANSSON,T.KARLBERG,S.KOL,T.KOTENYOVA,AUTH 4 M.MOCHE,T.K.NIELSEN,T.NYMAN,C.PERSSON,H.SCHULER,P.SCHUTZ,AUTH 5 M.I.SIPONEN,A.G.THORSELL,S.VAN DER BERG,E.WAHLBERG,AUTH 6 J.WEIGELT,M.WISNIEWSKA,P.NORDLUNDTITL CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE 25 KDA SUBUNITTITL 2 AND THE […]