Assessment of Structural Intolerance and Durability
General Structure Information 2pso STARD13 human stard13 (dlc2) lipid transfer and protein localization domain 2.8Å AUTH A.G.THORSELL,W.H.LEE,C.PERSSON,M.I.SIPONEN,M.NILSSON,AUTH 2 R.D.BUSAM,T.KOTENYOVA,H.SCHULER,L.LEHTIOTITL COMPARATIVE STRUCTURAL ANALYSIS OF LIPID BINDING STARTTITL 2 DOMAINS.REF PLOS ONE V. 6 19521 2011REFN ESSN 1932-6203PMID 21738568DOI 10.1371/JOURNAL.PONE.0019521 Variant Set Distributions Mapped Variants
General Structure Information 2jis CSAD human cysteine sulfinic acid decarboxylase (csad) in complex with plp. 1.6Å AUTH R.COLLINS,M.MOCHE,C.ARROWSMITH,H.BERGLUND,R.BUSAM,AUTH 2 L.G.DAHLGREN,A.EDWARDS,S.FLODIN,A.FLORES,AUTH 3 S.GRASLUND,M.HAMMARSTROM,B.M.HALLBERG,I.JOHANSSON,AUTH 4 A.KALLAS,T.KARLBERG,T.KOTENYOVA,L.LEHTIO,AUTH 5 P.NORDLUND,T.NYMAN,D.OGG,C.PERSSON,J.SAGEMARK,AUTH 6 P.STENMARK,M.SUNDSTROM,A.G.THORSELL,L.TRESAUGUES,AUTH 7 S.VAN DEN BERG,J.WEIGELT,M.WELIN,AUTH 8 L.HOLMBERG-SCHIAVONETITL THE CRYSTAL STRUCTURE OF HUMAN CYSTEINE SULFINICTITL 2 ACID DECARBOXYLASE (CSAD)REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 3bin EPB41L3 structure of the dal-1 and tslc1 (372-383) complex 2.3Å AUTH R.D.BUSAM,A.-G.THORSELL,A.FLORES,M.HAMMARSTROM,C.PERSSON,AUTH 2 B.OBRINK,B.M.HALLBERGTITL STRUCTURAL BASIS OF TUMOR SUPPRESSOR IN LUNG CANCER 1TITL 2 (TSLC1) BINDING TO DIFFERENTIALLY EXPRESSED INTITL 3 ADENOCARCINOMA OF THE LUNG (DAL-1/4.1B)REF J.BIOL.CHEM. V. 286 4511 2011REFN ISSN 0021-9258PMID 21131357DOI 10.1074/JBC.M110.174011 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 1wfg RIMS2 pdz domain of human rim2b -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL PDZ DOMAIN OF HUMAN RIM2BREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3evx UFC1 crystal structure of the human e2-like ubiquitin-fold modifier conjugating enzyme 1 (ufc1). northeast structural genomics consortium target hr41 2.54Å AUTH G.LIU,F.FOROUHAR,A.ELETSKY,H.S.ATREYA,J.M.ARAMINI,AUTH 2 R.XIAO,Y.J.HUANG,M.ABASHIDZE,J.SEETHARAMAN,J.LIU,AUTH 3 B.ROST,T.ACTON,G.T.MONTELIONE,J.F.HUNT,T.SZYPERSKITITL NMR AND X-RAY STRUCTURES OF HUMAN E2-LIKETITL 2 UBIQUITIN-FOLD MODIFIER CONJUGATING ENZYME 1TITL 3 (UFC1) REVEAL STRUCTURAL AND FUNCTIONALTITL 4 CONSERVATION IN THE METAZOAN UFM1-UBA5-UFC1TITL […]
General Structure Information 2qz4 SPG7 human paraplegin, aaa domain in complex with adp 2.22Å AUTH T.KARLBERG,S.VAN DEN BERG,M.HAMMARSTROM,J.SAGEMARK,AUTH 2 I.JOHANSSON,L.HOLMBERG-SCHIAVONE,H.SCHULERTITL CRYSTAL STRUCTURE OF THE ATPASE DOMAIN OF THE HUMAN AAA+TITL 2 PROTEIN PARAPLEGIN/SPG7.REF PLOS ONE V. 4 E6975 2009REFN ESSN 1932-6203PMID 19841671DOI 10.1371/JOURNAL.PONE.0006975 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2dgx KIAA0430 solution structure of the rna recognition motif in kiaa0430 protein -1.0Å AUTH C.ABE,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,M.SHIROUZU,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RNA RECOGNITION MOTIF INTITL 2 KIAA0430 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1ujd PCLO solution structure of rsgi ruh-003, a pdz domain of hypothetical kiaa0559 protein from human cdna -1.0Å AUTH W.OHASHI,H.HIROTA,T.YAMAZAKI,Y.MUTO,S.YOKOYAMATITL SOLUTION STRUCTURE OF RSGI RUH-003, A PDZ DOMAINTITL 2 OF HYPOTHETICAL KIAA0559 PROTEIN FROM HUMAN CDNAREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2diu KIAA0430 solution structure of the rrm domain of kiaa0430 protein -1.0Å AUTH W.DANG,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TERADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RRM DOMAIN OF KIAA0430TITL 2 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3l43 DNM3 crystal structure of the dynamin 3 gtpase domain bound with gdp 2.27Å AUTH S.YANG,W.TEMPEL,Y.TONG,L.NEDYALKOVA,X.GUAN,L.CROMBET,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,A.BOCHKAREV,AUTH 3 H.PARKTITL CRYSTAL STRUCTURE OF THE DYNAMIN 3 GTPASE DOMAIN BOUND WITHTITL 2 GDPREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants