Assessment of Structural Intolerance and Durability
General Structure Information 2okn PEPD crystal strcture of human prolidase 2.45Å AUTH U.MUELLER,F.H.NIESEN,Y.ROSKE,F.GOETZ,J.BEHLKE,K.BUESSOW,AUTH 2 U.HEINEMANNTITL CRYSTAL STRUCTURE OF HUMAN PROLIDASE: THE MOLECULAR BASIS OFTITL 2 PD DISEASE.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2fc8 NCL solution structure of the rrm_1 domain of ncl protein -1.0Å AUTH W.DANG,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TERADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RRM_1 DOMAIN OF NCLTITL 2 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4dnl PRKCA crystal structure of a c2 domain of a protein kinase c alpha (prkca) from homo sapiens at 1.90 a resolution 1.9Å AUTH JOINT CENTER FOR STRUCTURAL GENOMICS (JCSG),AUTH 2 PARTNERSHIP FOR T-CELL BIOLOGY (TCELL)TITL CRYSTAL STRUCTURE OF A C2 DOMAIN OF A PROTEIN KINASE C ALPHATITL 2 (PRKCA) FROM HOMO […]
General Structure Information 1×59 HARS solution structures of the whep-trs domain of human histidyl-trna synthetase -1.0Å AUTH N.NAMEKI,A.SASAGAWA,T.TOMIZAWA,S.KOSHIBA,M.INOUE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURES OF THE WHEP-TRS DOMAIN OFTITL 2 HUMAN HISTIDYL-TRNA SYNTHETASEREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2yqf ANK1 solution structure of the death domain of ankyrin-1 -1.0Å AUTH W.TANABE,S.SUZUKI,Y.MUTO,M.INOUE,T.KIGAWA,T.TERADA,AUTH 2 M.SHIROUZU,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE DEATH DOMAIN OF ANKYRIN-1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1fd0 RARG isotype selectivity of the human retinoic acid nuclear receptor hrar: the complex with the rargamma-selective retinoid sr11254 1.38Å AUTH B.KLAHOLZ,D.MORASTITL C-H…O HYDROGEN BONDS IN THE NUCLEAR RECEPTORTITL 2 RARGAMMA–A POTENTIAL TOOL FOR DRUG SELECTIVITY.REF STRUCTURE V. 10 1197 2002REFN ISSN 0969-2126PMID 12220491DOI 10.1016/S0969-2126(02)00828-6 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 1uwy CPM crystal structure of human carboxypeptidase m 3.0Å AUTH D.REVERTER,K.MASKOS,F.TAN,R.SKIDGEL,W.BODETITL CRYSTAL STRUCTURE OF HUMAN CARBOXYPEPTIDASE M, ATITL 2 MEMBRANE-BOUND ENZYME THAT REGULATES PEPTIDETITL 3 HORMONE ACTIVITYREF J.MOL.BIOL. V. 338 257 2004REFN ISSN 0022-2836PMID 15066430DOI 10.1016/J.JMB.2004.02.058 Variant Set Distributions Mapped Variants
General Structure Information 2d85 LCP1 solution structure of the fourth ch domain from human l- plastin -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FOURTH CH DOMAIN FROMTITL 2 HUMAN L-PLASTINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1z6x ARF4 structure of human adp-ribosylation factor 4 2.7Å AUTH A.ATANASSOVA,J.CHOE,C.ARROWSMITH,A.EDWARDS,AUTH 2 M.SUNDSTROM,A.BOCHKAREV,H.PARKTITL STRUCTURE OF HUMAN ADP-RIBOSYLATION FACTOR 4REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2fc9 NCL solution structure of the rrm_1 domain of ncl protein -1.0Å AUTH W.DANG,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TERADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE RRM_1 DOMAIN OF NCLTITL 2 PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants