Assessment of Structural Intolerance and Durability
General Structure Information 2dyq APBB3 crystal structure of the c-terminal phophotyrosine interaction domain of human apbb3 3.1Å AUTH S.SAIJO,A.NISHINO,S.KISHISHITA,M.SHIROUZU,S.YOKOYAMATITL CRYSTAL STRUCTURE OF THE C-TERMINAL PHOPHOTYROSINETITL 2 INTERACTION DOMAIN OF HUMAN APBB3REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2q80 GGPS1 crystal structure of human geranylgeranyl pyrophosphate synthase bound to ggpp 2.7Å AUTH K.L.KAVANAGH,J.E.DUNFORD,G.BUNKOCZI,R.G.RUSSELL,U.OPPERMANNTITL THE CRYSTAL STRUCTURE OF HUMAN GERANYLGERANYL PYROPHOSPHATETITL 2 SYNTHASE REVEALS A NOVEL HEXAMERIC ARRANGEMENT ANDTITL 3 INHIBITORY PRODUCT BINDINGREF J.BIOL.CHEM. V. 281 22004 2006REFN ISSN 0021-9258PMID 16698791DOI 10.1074/JBC.M602603200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]
General Structure Information 2gf9 RAB3D crystal structure of human rab3d in complex with gdp 1.53Å AUTH B.HONG,J.WANG,L.SHEN,W.TEMPEL,R.LANDRY,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,M.SUNDSTROM,J.WEIGELT,AUTH 3 A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF HUMAN RAB3D IN COMPLEX WITHTITL 2 GDPREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2kl7 EFEMP2 solution nmr structure of the egf-like 1 domain of human fibulin-4. northeast structural genomics target hr6275 -1.0Å AUTH P.ROSSI,Y.CHIANG,S.ANDERSON,G.T.MONTELIONETITL SOLUTION NMR STRUCTURE OF THE EGF-LIKE 1 DOMAIN OFTITL 2 HUMAN FIBULIN-4. NORTHEAST STRUCTURAL GENOMICSTITL 3 TARGET HR6275REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2coe DNTT solution structure of brct domain of terminal deoxynucleotidyltransferase -1.0Å AUTH T.NAGASHIMA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF BRCT DOMAIN OF TERMINALTITL 2 DEOXYNUCLEOTIDYLTRANSFERASEREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ytv CSDE1 solution structure of the fifth cold-shock domain of the human kiaa0885 protein (unr protein) -1.0Å AUTH A.K.GORONCY,S.KOSHIBA,N.TOCHIO,T.TOMIZAWA,M.INOUE,AUTH 2 S.WATANABE,T.HARADA,A.TANAKA,O.OHARA,T.KIGAWA,S.YOKOYAMATITL THE NMR SOLUTION STRUCTURES OF THE FIVE CONSTITUENTTITL 2 COLD-SHOCK DOMAINS (CSD) OF THE HUMAN UNR (UPSTREAM OFTITL 3 N-RAS) PROTEIN.REF J.STRUCT.FUNCT.GENOM. V. 11 181 2010REFN ISSN 1345-711XPMID 20213426DOI 10.1007/S10969-010-9081-Z Variant […]
General Structure Information 2gqm SCO1 solution structure of human cu(i)-sco1 -1.0Å AUTH L.BANCI,I.BERTINI,V.CALDERONE,S.CIOFI-BAFFONI,AUTH 2 S.MANGANI,M.MARTINELLI,P.PALUMAA,S.WANGTITL A HINT FOR THE FUNCTION OF HUMAN SCO1 FROMTITL 2 DIFFERENT STRUCTURES.REF PROC.NATL.ACAD.SCI.USA V. 103 8595 2006REFN ISSN 0027-8424PMID 16735468DOI 10.1073/PNAS.0601375103 Variant Set Distributions Mapped Variants
General Structure Information 2di9 FLNB solution structure of the 9th filamin domain from human filamin-b -1.0Å AUTH T.TOMIZAWA,S.KOSHIBA,S.WATANABE,T.HARADA,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 9TH FILAMIN DOMAIN FROMTITL 2 HUMAN FILAMIN-BREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ax4 PAPSS2 crystal structure of the kinase domain of human 3- phosphoadenosine 5-phosphosulphate synthetase 2 2.5Å AUTH W.M.RABEH,L.NEDYALKOVA,S.ISMAIL,H.PARK,AUTH 2 C.ARROWSMITH,A.EDWARDS,M.SUNDSTROM,J.WEIGELT,AUTH 3 A.BOCHKAREVTITL CRYSTAL STRUCTURE OF THE KINASE DOMAIN OF PAPSS 2REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3lrq TRIM37 crystal structure of the u-box domain of human ubiquitin- protein ligase (e3), northeast structural genomics consortium target hr4604d. 2.29Å AUTH A.KUZIN,Y.CHEN,J.SEETHARAMAN,M.MAO,R.XIAO,AUTH 2 C.CICCOSANTI,R.SHASTRY,J.K.EVERETT,R.NAIR,AUTH 3 T.B.ACTON,B.ROST,G.T.MONTELIONE,L.TONG,J.F.HUNTTITL E3 UBIQUITIN-PROTEIN LIGASE RING DOMAIN FROM HUMANTITL 2 TRIPARTITE MOTIF-CONTAINING PROTEIN 37 (TRIM37),TITL 3 NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGETTITL 4 HR4604D.REF TO BE PUBLISHEDREFN Variant […]