Assessment of Structural Intolerance and Durability
General Structure Information 1rqd DHPS deoxyhypusine synthase holoenzyme in its low ionic strength, high ph crystal form with the inhibitor gc7 bound in the active site 3.0Å AUTH T.C.UMLAND,E.C.WOLFF,M.-H.PARK,D.R.DAVIESTITL A NEW CRYSTAL STRUCTURE OF DEOXYHYPUSINE SYNTHASE REVEALSTITL 2 THE CONFIGURATION OF THE ACTIVE ENZYME AND OF ANTITL 3 ENZYME-NAD-INHIBITOR TERNARY COMPLEXREF J.BIOL.CHEM. V. 279 28697 […]
General Structure Information 3c6k SMS crystal structure of human spermine synthase in complex with spermidine and 5-methylthioadenosine 1.95Å AUTH H.WU,J.MIN,H.ZENG,D.E.MCCLOSKEY,Y.IKEGUCHI,AUTH 2 P.LOPPNAU,A.J.MICHAEL,A.E.PEGG,A.N.PLOTNIKOVTITL CRYSTAL STRUCTURE OF HUMAN SPERMINE SYNTHASE:TITL 2 IMPLICATIONS OF SUBSTRATE BINDING AND CATALYTICTITL 3 MECHANISM.REF J.BIOL.CHEM. V. 283 16135 2008REFN ISSN 0021-9258PMID 18367445DOI 10.1074/JBC.M710323200 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants