Assessment of Structural Intolerance and Durability
General Structure Information 3qf2 NLRP3 crystal structure of nalp3 pyd 1.7Å AUTH J.Y.BAE,H.H.PARKTITL CRYSTAL STRUCTURE OF NALP3 PROTEIN PYRIN DOMAIN (PYD) ANDTITL 2 ITS IMPLICATIONS IN INFLAMMASOME ASSEMBLYREF J.BIOL.CHEM. V. 286 39528 2011REFN ISSN 0021-9258PMID 21880711DOI 10.1074/JBC.M111.278812 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2hm2 PYDC1 solution structure of asc2 -1.0Å AUTH A.NATARAJAN,R.GHOSE,J.M.HILLTITL STRUCTURE AND DYNAMICS OF ASC2, A PYRINTITL 2 DOMAIN-ONLY PROTEIN THAT REGULATES INFLAMMATORYTITL 3 SIGNALINGREF J.BIOL.CHEM. V. 281 31863 2006REFN ISSN 0021-9258PMID 16905547DOI 10.1074/JBC.M605458200 Variant Set Distributions Mapped Variants
General Structure Information 3g4h RGN crystal structure of human senescence marker protein-30 (zinc bound) 1.92Å AUTH S.CHAKRABORTI,B.J.BAHNSONTITL CRYSTAL STRUCTURE OF HUMAN SENESCENCE MARKER PROTEIN 30:TITL 2 INSIGHTS LINKING STRUCTURAL, ENZYMATIC, AND PHYSIOLOGICALTITL 3 FUNCTIONS .REF BIOCHEMISTRY V. 49 3436 2010REFN ISSN 0006-2960PMID 20329768DOI 10.1021/BI9022297 Variant Set Distributions Mapped Variants
General Structure Information 4egc SIX1 crystal structure of mbp-fused human six1 bound to human eya2 eya domain 1.99Å AUTH A.N.PATRICK,J.H.CABRERA,A.L.SMITH,X.S.CHEN,H.L.FORD,R.ZHAOTITL STRUCTURE-FUNCTION ANALYSES OF THE HUMAN SIX1-EYA2 COMPLEXTITL 2 REVEAL INSIGHTS INTO METASTASIS AND BOR SYNDROME.REF NAT.STRUCT.MOL.BIOL. V. 20 447 2013REFN ISSN 1545-9993PMID 23435380DOI 10.1038/NSMB.2505 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped […]
General Structure Information 4egc SIX1 crystal structure of mbp-fused human six1 bound to human eya2 eya domain 1.99Å AUTH A.N.PATRICK,J.H.CABRERA,A.L.SMITH,X.S.CHEN,H.L.FORD,R.ZHAOTITL STRUCTURE-FUNCTION ANALYSES OF THE HUMAN SIX1-EYA2 COMPLEXTITL 2 REVEAL INSIGHTS INTO METASTASIS AND BOR SYNDROME.REF NAT.STRUCT.MOL.BIOL. V. 20 447 2013REFN ISSN 1545-9993PMID 23435380DOI 10.1038/NSMB.2505 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped […]
General Structure Information 4egc SIX1 crystal structure of mbp-fused human six1 bound to human eya2 eya domain 1.99Å AUTH A.N.PATRICK,J.H.CABRERA,A.L.SMITH,X.S.CHEN,H.L.FORD,R.ZHAOTITL STRUCTURE-FUNCTION ANALYSES OF THE HUMAN SIX1-EYA2 COMPLEXTITL 2 REVEAL INSIGHTS INTO METASTASIS AND BOR SYNDROME.REF NAT.STRUCT.MOL.BIOL. V. 20 447 2013REFN ISSN 1545-9993PMID 23435380DOI 10.1038/NSMB.2505 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped […]