Assessment of Structural Intolerance and Durability
General Structure Information 2ekh SH3PXD2A solution structures of the sh3 domain of human kiaa0418 -1.0Å AUTH M.SATO,N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURES OF THE SH3 DOMAIN OF HUMANTITL 2 KIAA0418REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3l4c DOCK1 structural basis of membrane-targeting by dock180 2.37Å AUTH L.PREMKUMAR,A.A.BOBKOV,M.PATEL,L.JAROSZEWSKI,L.A.BANKSTON,AUTH 2 B.STEC,K.VUORI,J.F.COTE,R.C.LIDDINGTONTITL STRUCTURAL BASIS OF MEMBRANE TARGETING BY THE DOCK180TITL 2 FAMILY OF RHO FAMILY GUANINE EXCHANGE FACTORS (RHO-GEFS).REF J.BIOL.CHEM. V. 285 13211 2010REFN ISSN 0021-9258PMID 20167601DOI 10.1074/JBC.M110.102517 Variant Set Distributions Mapped Variants
General Structure Information 3f31 SPTAN1 crystal structure of the n-terminal region of alphaii-spectrin tetramerization domain 2.3Å AUTH S.MEHBOOB,Y.SONG,M.WITEK,F.LONG,B.D.SANTARSIERO,AUTH 2 M.E.JOHNSON,L.W.FUNGTITL CRYSTAL STRUCTURE OF THE NONERYTHROID ALPHA-SPECTRINTITL 2 TETRAMERIZATION SITE REVEALS DIFFERENCES BETWEEN ERYTHROIDTITL 3 AND NONERYTHROID SPECTRIN TETRAMER FORMATION.REF J.BIOL.CHEM. V. 285 14572 2010REFN ISSN 0021-9258PMID 20228407DOI 10.1074/JBC.M109.080028 Variant Set Distributions Mapped Variants
General Structure Information 2byg DLG2 2nd pdz domain of discs large homologue 2 1.85Å AUTH J.M.ELKINS,E.PAPAGRIGORIOU,G.BERRIDGE,X.YANG,C.PHILLIPS,AUTH 2 C.GILEADI,C.SAVITSKY,D.A.DOYLETITL STRUCTURE OF PICK1 AND OTHER PDZ DOMAINS OBTAINED WITH THETITL 2 HELP OF SELF-BINDING C-TERMINAL EXTENSIONS.REF PROTEIN SCI. V. 16 683 2007REFN ISSN 0961-8368PMID 17384233DOI 10.1110/PS.062657507 Variant Set Distributions Mapped Variants
General Structure Information 1ujy ARHGEF6 solution structure of sh3 domain in rac/cdc42 guanine nucleotide exchange factor(gef) 6 -1.0Å AUTH F.HE,Y.MUTO,H.UDA,S.KOSHIBA,M.SHIROUZU,T.TERADA,AUTH 2 T.KIGAWA,M.INOUE,T.YABUKI,M.AOKI,E.SEKI,T.MATSUDA,AUTH 3 H.HIROTA,M.YOSHIDA,N.KOBAYASHI,A.TANAKA,T.OSANAI,AUTH 4 Y.MATSUO,O.OHARA,T.NAGASE,R.KIKUNO,M.NAGAYAMA,AUTH 5 S.YOKOYAMATITL SOLUTION STRUCTURE OF SH3 DOMAIN IN RAC/CDC42TITL 2 GUANINE NUCLEOTIDE EXCHANGE FACTOR(GEF) 6REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3fb2 SPTAN1 crystal structure of the human brain alpha spectrin repeats 15 and 16. northeast structural genomics consortium target hr5563a. 2.3Å AUTH S.M.VOROBIEV,M.SU,J.SEETHARAMAN,R.SHASTRY,AUTH 2 E.L.FOOTE,C.CICCOSANTI,H.JANJUA,R.XIAO,T.B.ACTON,AUTH 3 G.T.MONTELIONE,L.TONG,J.F.HUNTTITL CRYSTAL STRUCTURE OF THE HUMAN BRAIN ALPHATITL 2 SPECTRIN REPEATS 15 AND 16.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2kgt PTK6 solution structure of sh3 domain of ptk6 -1.0Å AUTH W.LEE,S.KOTITL THE SOLUTION STRUCTURE OF SH3 DOMAIN OF PTK6REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ct4 TRIP10 solution strutcure of the sh3 domain of the cdc42- interacting protein 4 -1.0Å AUTH K.MIYAMOTO,T.TOMIZAWA,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUTCURE OF THE SH3 DOMAIN OF THETITL 2 CDC42-INTERACTING PROTEIN 4REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1×69 CTTN solution structures of the sh3 domain of human src substrate cortactin -1.0Å AUTH M.SATO,N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURES OF THE SH3 DOMAIN OF HUMAN SRCTITL 2 SUBSTRATE CORTACTINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3i35 LASP1 human sh3 domain of protein lasp1 1.4Å AUTH M.I.SIPONEN,A.K.ROOS,C.H.ARROWSMITH,H.BERGLUND,C.BOUNTRA,AUTH 2 R.COLLINS,A.M.EDWARDS,S.FLODIN,A.FLORES,S.GRASLUND,AUTH 3 M.HAMMARSTROM,A.JOHANSSON,I.JOHANSSON,T.KARLBERG,AUTH 4 T KOTENYOVA,A.KOTZSCH,T.KRAGH NIELSEN,M.MOCHE,T.NYMAN,AUTH 5 C.PERSSON,J.SAGEMARK,H.SCHUELER,P.SCHUTZ,A.G.THORSELL,AUTH 6 L.TRESAUGUES,S.VAN DEN BERG,J.WEIGELT,M.WELIN,M.WISNIEWSKA,AUTH 7 P.NORDLUNDTITL HUMAN SH3 DOMAIN OF PROTEIN LASP1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants