Assessment of Structural Intolerance and Durability
General Structure Information 1n83 RORA crystal structure of the complex between the orphan nuclear hormone receptor ror(alpha)-lbd and cholesterol 1.63Å AUTH J.A.KALLEN,J.M.SCHLAEPPI,F.BITSCH,S.GEISSE,AUTH 2 M.GEISER,I.DELHON,B.FOURNIERTITL X-RAY STRUCTURE OF HROR(ALPHA) LBD AT 1.63A:TITL 2 STRUCTURAL AND FUNCTIONAL DATA THAT CHOLESTEROL ORTITL 3 A CHOLESTEROL DERIVATIVE IS THE NATURAL LIGAND OFTITL 4 ROR(ALPHA)REF STRUCTURE V. 10 1697 2002REFN […]
General Structure Information 1n3h SHC1 coupling of folding and binding in the ptb domain of the signaling protein shc -1.0Å AUTH A.FAROOQ,L.ZENG,K.S.YAN,K.S.RAVICHANDRAN,M.-M.ZHOUTITL COUPLING OF FOLDING AND BINDING IN THE PTB DOMAINTITL 2 OF THE SIGNALING PROTEIN SHCREF STRUCTURE V. 11 905 2003REFN ISSN 0969-2126PMID 12906822DOI 10.1016/S0969-2126(03)00134-5 Variant Set Distributions Mapped Variants
General Structure Information 3cjw NR2F2 crystal structure of the human coup-tfii ligand binding domain 1.48Å AUTH S.W.KRUSE,K.SUINO-POWELL,X.E.ZHOU,J.E.KRETSCHMAN,AUTH 2 R.REYNOLDS,C.VONRHEIN,Y.XU,L.WANG,S.Y.TSAI,AUTH 3 M.J.TSAI,H.E.XUTITL IDENTIFICATION OF COUP-TFII ORPHAN NUCLEARTITL 2 RECEPTOR AS A RETINOIC ACID-ACTIVATED RECEPTOR.REF PLOS BIOL. V. 6 E227 2008REFN ISSN 1544-9173PMID 18798693DOI 10.1371/JOURNAL.PBIO.0060227 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 1msv AMD1 the s68a s-adenosylmethionine decarboxylase proenzyme processing mutant. 1.75Å AUTH W.D.TOLBERT,Y.ZHANG,S.E.COTTET,E.M.BENNETT,AUTH 2 J.L.EKSTROM,A.E.PEGG,S.E.EALICKTITL MECHANISM OF HUMAN S-ADENOSYLMETHIONINETITL 2 DECARBOXYLASE PROENZYME PROCESSING AS REVEALED BYTITL 3 THE STRUCTURE OF THE S68A MUTANT.REF BIOCHEMISTRY V. 42 2386 2003REFN ISSN 0006-2960PMID 12600205DOI 10.1021/BI0268854 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]