General Structure Information
| PDB ID | 1msv |
| HGNC Gene Label(s) | AMD1 |
| Structure Name | the s68a s-adenosylmethionine decarboxylase proenzyme processing mutant. |
| Resolution | 1.75Å |
| Reference | AUTH W.D.TOLBERT,Y.ZHANG,S.E.COTTET,E.M.BENNETT,AUTH 2 J.L.EKSTROM,A.E.PEGG,S.E.EALICKTITL MECHANISM OF HUMAN S-ADENOSYLMETHIONINETITL 2 DECARBOXYLASE PROENZYME PROCESSING AS REVEALED BYTITL 3 THE STRUCTURE OF THE S68A MUTANT.REF BIOCHEMISTRY V. 42 2386 2003REFN ISSN 0006-2960PMID 12600205DOI 10.1021/BI0268854 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 319 |
| Number Of SNVs | 55 |
| Number Of Permutations | 25455 |
| Optimal Distance Threshold | 15.0 |
| K Statistic | 0.115 |
| p-value | 0.0 |
COSMIC
| Number Of Residues | 319 |
| Number Of SNVs | 5 |
| Number Of Permutations | 639 |
| Optimal Distance Threshold | 25.0 |
| K Statistic | 0.2 |
| p-value | 0.232 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 55 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 25.0 |
| K Statistic | -0.206 |
| p-value | 0.437 |
Pathogenic Proximity Analysis
COSMIC PathProx Analysis
