Assessment of Structural Intolerance and Durability
General Structure Information 2kdp SAP30 solution structure of the sap30 zinc finger motif -1.0Å AUTH Y.HE,R.IMHOFF,A.SAHU,I.RADHAKRISHNANTITL SOLUTION STRUCTURE OF A NOVEL ZINC FINGER MOTIF INTITL 2 THE SAP30 POLYPEPTIDE OF THE SIN3 COREPRESSORTITL 3 COMPLEX AND ITS POTENTIAL ROLE IN NUCLEIC ACIDTITL 4 RECOGNITIONREF NUCLEIC ACIDS RES. V. 37 2142 2009REFN ISSN 0305-1048PMID 19223330DOI 10.1093/NAR/GKP051 […]
General Structure Information 3k27 EED complex structure of eed and trimethylated h3k9 1.76Å AUTH C.XU,C.BIAN,W.YANG,M.GALKA,H.OUYANG,C.CHEN,W.QIU,H.LIU,AUTH 2 A.E.JONES,F.MACKENZIE,P.PAN,S.S.LI,H.WANG,J.MINTITL BINDING OF DIFFERENT HISTONE MARKS DIFFERENTIALLY REGULATESTITL 2 THE ACTIVITY AND SPECIFICITY OF POLYCOMB REPRESSIVE COMPLEXTITL 3 2 (PRC2).REF PROC.NATL.ACAD.SCI.USA V. 107 19266 2010REFN ISSN 0027-8424PMID 20974918DOI 10.1073/PNAS.1008937107 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 3dal PRDM1 methyltransferase domain of human pr domain-containing protein 1 1.65Å AUTH H.ZENG,M.F.AMAYA,T.ANTOSHENKO,A.DONG,P.LOPPNAU,AUTH 2 A.BOCHKAREV,J.MIN,A.N.PLOTNIKOV,H.WUTITL THE CRYSTAL STRUCTURE OF METHYLTRANSFERASE DOMAINTITL 2 OF HUMAN PR DOMAIN-CONTAINING PROTEIN 1REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3h7h SUPT5H crystal structure of the human transcription elongation factor dsif, hspt4/hspt5 (176-273) 1.55Å AUTH S.WENZEL,B.M.MARTINS,P.ROSCH,B.M.WOHRLTITL CRYSTAL STRUCTURE OF THE HUMAN TRANSCRIPTION ELONGATIONTITL 2 FACTOR DSIF HSPT4 SUBUNIT IN COMPLEX WITH THE HSPT5TITL 3 DIMERIZATION INTERFACEREF BIOCHEM.J. V. 425 373 2010REFN ISSN 0264-6021PMID 19860741DOI 10.1042/BJ20091422 Variant Set Distributions Mapped Variants
General Structure Information 3hfh TCERG1 crystal structure of tandem ff domains 2.7Å AUTH M.LU,J.YANG,Z.REN,S.SABUI,A.ESPEJO,M.T.BEDFORD,AUTH 2 R.H.JACOBSON,D.JERUZALMI,J.S.MCMURRAY,X.CHENTITL CRYSTAL STRUCTURE OF THE THREE TANDEM FF DOMAINS OFTITL 2 THE TRANSCRIPTION ELONGATION REGULATOR CA150.REF J.MOL.BIOL. V. 393 397 2009REFN ISSN 0022-2836PMID 19660470DOI 10.1016/J.JMB.2009.07.086 Variant Set Distributions Mapped Variants
General Structure Information 1h6f TBX3 human tbx3, a transcription factor responsible for ulnar-mammary syndrome , bound to a palindromic dna site 1.7Å AUTH M.COLL,J.G.SEIDMAN,C.W.MULLERTITL STRUCTURE OF THE DNA-BOUND T-BOX DOMAIN OF HUMANTITL 2 TBX3, A TRANSCRIPTION FACTOR RESPONSIBLE FORTITL 3 ULNAR- MAMMARY SYNDROMEREF STRUCTURE V. 10 343 2002REFN ISSN 0969-2126PMID 12005433DOI 10.1016/S0969-2126(02)00722-0 Variant Set Distributions […]