Assessment of Structural Intolerance and Durability
General Structure Information 2vyt SCML2 the mbt repeats of human scml2 bind to peptides containing mono methylated lysine. 1.9Å AUTH C.M.SANTIVERI,B.C.LECHTENBERG,M.D.ALLEN,AUTH 2 A.SATHYAMURTHY,A.M.JAULENT,S.M.V.FREUND,M.BYCROFTTITL THE MALIGNANT BRAIN TUMOR REPEATS OF HUMAN SCML2TITL 2 BIND TO PEPTIDES CONTAINING MONOMETHYLATED LYSINE.REF J.MOL.BIOL. V. 382 1107 2008REFN ISSN 0022-2836PMID 18706910DOI 10.1016/J.JMB.2008.07.081 Variant Set Distributions Mapped Variants
General Structure Information 3dad FHOD1 crystal structure of the n-terminal regulatory domains of the formin fhod1 2.3Å AUTH A.SCHULTE,B.STOLP,A.SCHONICHEN,O.PYLYPENKO,A.RAK,AUTH 2 O.T.FACKLER,M.GEYERTITL THE HUMAN FORMIN FHOD1 CONTAINS A BIPARTITETITL 2 STRUCTURE OF FH3 AND GTPASE-BINDING DOMAINSTITL 3 REQUIRED FOR ACTIVATION.REF STRUCTURE V. 16 1313 2008REFN ISSN 0969-2126PMID 18786395DOI 10.1016/J.STR.2008.06.008 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 3d9i SCAF8 snapshots of the rna processing factor scaf8 bound to different phosphorylated forms of the carboxy-terminal domain of rna-polymerase ii 1.91Å AUTH R.BECKER,B.LOLL,A.MEINHARTTITL SNAPSHOTS OF THE RNA PROCESSING FACTOR SCAF8 BOUND TOTITL 2 DIFFERENT PHOSPHORYLATED FORMS OF THE CARBOXYL-TERMINALTITL 3 DOMAIN OF RNA POLYMERASE II.REF J.BIOL.CHEM. V. 283 22659 2008REFN ISSN […]
General Structure Information 3i2n WDR92 crystal structure of wd40 repeats protein wdr92 1.95Å AUTH C.XU,J.MINTITL STRUCTURE AND FUNCTION OF WD40 DOMAIN PROTEINS.REF PROTEIN CELL V. 2 202 2011REFN ISSN 1674-800XPMID 21468892DOI 10.1007/S13238-011-1018-1 Variant Set Distributions Mapped Variants
General Structure Information 2vge PPP1R13L crystal structure of the c-terminal region of human iaspp 2.1Å AUTH R.A.ROBINSON,X.LU,E.Y.JONES,C.SIEBOLDTITL BIOCHEMICAL AND STRUCTURAL STUDIES OF ASPPTITL 2 PROTEINS REVEAL DIFFERENTIAL BINDING TO P53, P63TITL 3 AND P73REF STRUCTURE V. 16 259 2008REFN ISSN 0969-2126PMID 18275817DOI 10.1016/J.STR.2007.11.012 Variant Set Distributions Mapped Variants
General Structure Information 2dm4 SORL1 solution structure of the second fn3 domain of human sorla/lr11 -1.0Å AUTH T.NAGASHIMA,C.KUROSAKI,M.YOSHIDA,F.HAYASHI,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND FN3 DOMAIN OFTITL 2 HUMAN SORLA/LR11REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 4hnm CTNNBL1 crystal structure of human catenin-beta-like 1 56 kda fragment 2.9Å AUTH X.HUANG,G.WANG,Y.WU,Z.DUTITL THE STRUCTURE OF FULL-LENGTH HUMAN CTNNBL1 REVEALS ATITL 2 DISTINCT MEMBER OF THE ARMADILLO-REPEAT PROTEIN FAMILY.REF ACTA CRYSTALLOGR.,SECT.D V. 69 1598 2013REFN ISSN 0907-4449PMID 23897482DOI 10.1107/S0907444913011360 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 3eu9 ZDHHC17 the ankyrin repeat domain of huntingtin interacting protein 14 1.99Å AUTH T.GAO,R.E.COLLINS,J.R.HORTON,X.ZHANG,R.ZHANG,A.DHAYALAN,AUTH 2 R.TAMAS,A.JELTSCH,X.CHENGTITL THE ANKYRIN REPEAT DOMAIN OF HUNTINGTIN INTERACTING PROTEINTITL 2 14 CONTAINS A SURFACE AROMATIC CAGE, A POTENTIAL SITE FORTITL 3 METHYL-LYSINE BINDING.REF PROTEINS V. 76 772 2009REFN ISSN 0887-3585PMID 19434754DOI 10.1002/PROT.22452 Variant Set Distributions Mapped Variants
General Structure Information 4k6j WAPAL human cohesin inhibitor wapl 2.62Å AUTH Z.OUYANG,G.ZHENG,J.SONG,D.M.BOREK,Z.OTWINOWSKI,AUTH 2 C.A.BRAUTIGAM,D.R.TOMCHICK,S.RANKIN,H.YUTITL STRUCTURE OF THE HUMAN COHESIN INHIBITOR WAPL.REF PROC.NATL.ACAD.SCI.USA V. 110 11355 2013REFN ISSN 0027-8424PMID 23776203DOI 10.1073/PNAS.1304594110 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1kt0 FKBP5 structure of the large fkbp-like protein, fkbp51, involved in steroid receptor complexes 2.7Å AUTH C.R.SINARS,J.CHEUNG-FLYNN,R.A.RIMERMAN,J.G.SCAMMELL,AUTH 2 D.F.SMITH,J.C.CLARDYTITL STRUCTURE OF THE LARGE FK506-BINDING PROTEIN FKBP51, ANTITL 2 HSP90-BINDING PROTEIN AND A COMPONENT OF STEROID RECEPTORTITL 3 COMPLEXESREF PROC.NATL.ACAD.SCI.USA V. 100 868 2003REFN ISSN 0027-8424PMID 12538866DOI 10.1073/PNAS.0231020100 Variant Set Distributions Ripley’s K […]