Assessment of Structural Intolerance and Durability
General Structure Information 1y6k IL10 crystal structure of human il-10 complexed with the soluble il-10r1 chain 2.52Å AUTH S.I.YOON,B.C.JONES,N.J.LOGSDON,M.R.WALTERTITL SAME STRUCTURE, DIFFERENT FUNCTION CRYSTALTITL 2 STRUCTURE OF THE EPSTEIN-BARR VIRUS IL-10 BOUND TOTITL 3 THE SOLUBLE IL-10R1 CHAIN.REF STRUCTURE V. 13 551 2005REFN ISSN 0969-2126PMID 15837194DOI 10.1016/J.STR.2005.01.016 Variant Set Distributions Mapped Variants
General Structure Information 3cxe CSF2RA structure of the gm-csf receptor complex 3.3Å AUTH G.HANSEN,T.R.HERCUS,B.J.MCCLURE,F.C.STOMSKI,M.DOTTORE,AUTH 2 J.POWELL,H.RAMSHAW,J.M.WOODCOCK,Y.XU,M.GUTHRIDGE,AUTH 3 W.J.MCKINSTRY,A.F.LOPEZ,M.W.PARKERTITL THE STRUCTURE OF THE GM-CSF RECEPTOR COMPLEX REVEALS ATITL 2 DISTINCT MODE OF CYTOKINE RECEPTOR ACTIVATIONREF CELL(CAMBRIDGE,MASS.) V. 134 496 2008REFN ISSN 0092-8674PMID 18692472DOI 10.1016/J.CELL.2008.05.053 Variant Set Distributions Mapped Variants
General Structure Information 3sgj FCGR3A unique carbohydrate-carbohydrate interactions are required for high affinity binding between fcgiii and antibodies lacking core fucose 2.2Å AUTH C.FERRARA,S.GRAU,C.JAGER,P.SONDERMANN,P.BRUNKER,I.WALDHAUER,AUTH 2 M.HENNIG,A.RUF,A.C.RUFER,M.STIHLE,P.UMANA,J.BENZTITL UNIQUE CARBOHYDRATE-CARBOHYDRATE INTERACTIONS ARE REQUIREDTITL 2 FOR HIGH AFFINITY BINDING BETWEEN FCGAMMARIII AND ANTIBODIESTITL 3 LACKING CORE FUCOSE.REF PROC.NATL.ACAD.SCI.USA V. 108 12669 2011REFN ISSN 0027-8424PMID 21768335DOI 10.1073/PNAS.1108455108 Variant Set […]