Assessment of Structural Intolerance and Durability
General Structure Information 2zne PDCD6 crystal structure of zn2+-bound form of des3-23alg-2 complexed with alix abs peptide 2.2Å AUTH H.SUZUKI,M.KAWASAKI,T.INUZUKA,M.OKUMURA,T.KAKIUCHI,AUTH 2 H.SHIBATA,S.WAKATSUKI,M.MAKITITL STRUCTURAL BASIS FOR CA(2+)-DEPENDENT FORMATION OFTITL 2 ALG-2/ALIX PEPTIDE COMPLEX: CA(2+)/EF3-DRIVENTITL 3 ARGININE SWITCH MECHANISMREF STRUCTURE V. 16 1562 2008REFN ISSN 0969-2126PMID 18940611DOI 10.1016/J.STR.2008.07.012 Variant Set Distributions Mapped Variants
General Structure Information 4j2c STX6 garp-snare interaction 1.8Å AUTH G.ABASCAL-PALACIOS,C.SCHINDLER,A.L.ROJAS,J.S.BONIFACINO,AUTH 2 A.HIERROTITL STRUCTURAL BASIS FOR THE INTERACTION OF THE GOLGI-ASSOCIATEDTITL 2 RETROGRADE PROTEIN COMPLEX WITH THE T-SNARE SYNTAXIN 6.REF STRUCTURE V. 21 1698 2013REFN ISSN 0969-2126PMID 23932592DOI 10.1016/J.STR.2013.06.025 Variant Set Distributions Mapped Variants
General Structure Information 4bxu PEX14 structure of pex14 in complex with pex5 lvxef motif -1.0Å AUTH A.NEUHAUS,H.KOOSHAPUR,J.WOLF,H.N.MEYER,T.MADL,J.SAIDOWSKY,AUTH 2 E.HAMBRUCH,A.LASSAM,M.JUNG,M.SATTLER,W.SCHLIEBS,R.ERDMANNTITL A NOVEL PEX14 INTERACTING SITE OF HUMAN PEX5 IS CRITICALTITL 2 FOR MATRIX PROTEIN IMPORT INTO PEROXISOMES.REF J.BIOL.CHEM. V. 289 437 2014REFN ISSN 0021-9258PMID 24235149DOI 10.1074/JBC.M113.499707 Variant Set Distributions Mapped Variants
General Structure Information 1xwi VPS4B crystal structure of vps4b 2.8Å AUTH A.SCOTT,H.Y.CHUNG,M.GONCIARZ-SWIATEK,G.C.HILL,AUTH 2 F.G.WHITBY,J.GASPAR,J.M.HOLTON,R.VISWANATHAN,AUTH 3 S.GHAFFARIAN,C.P.HILL,W.I.SUNDQUISTTITL STRUCTURAL AND MECHANISTIC STUDIES OF VPS4 PROTEINSREF EMBO J. V. 24 3658 2005REFN ISSN 0261-4189PMID 16193069DOI 10.1038/SJ.EMBOJ.7600818 Variant Set Distributions Mapped Variants
General Structure Information 3eh1 SEC24B crystal structure of the human copii-coat protein sec24b 1.8Å AUTH J.D.MANCIAS,J.GOLDBERGTITL STRUCTURAL BASIS OF CARGO MEMBRANE PROTEINTITL 2 DISCRIMINATION BY THE HUMAN COPII COAT MACHINERY.REF EMBO J. V. 27 2918 2008REFN ISSN 0261-4189PMID 18843296DOI 10.1038/EMBOJ.2008.208 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3kq4 CUBN structure of intrinsic factor-cobalamin bound to its receptor cubilin 3.3Å AUTH C.B.ANDERSEN,M.MADSEN,T.STORM,S.K.MOESTRUP,G.R.ANDERSENTITL STRUCTURAL BASIS FOR RECEPTOR RECOGNITION OFTITL 2 VITAMIN-B(12)-INTRINSIC FACTOR COMPLEXES.REF NATURE V. 464 445 2010REFN ISSN 0028-0836PMID 20237569DOI 10.1038/NATURE08874 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3nby SNUPN crystal structure of the pki nes-crm1-rangtp nuclear export complex 3.42Å AUTH T.GUTTLER,T.MADL,P.NEUMANN,D.DEICHSEL,L.CORSINI,T.MONECKE,AUTH 2 R.FICNER,M.SATTLER,D.GORLICHTITL NES CONSENSUS REDEFINED BY STRUCTURES OF PKI-TYPE ANDTITL 2 REV-TYPE NUCLEAR EXPORT SIGNALS BOUND TO CRM1.REF NAT.STRUCT.MOL.BIOL. V. 17 1367 2010REFN ISSN 1545-9993PMID 20972448DOI 10.1038/NSMB.1931 Variant Set Distributions Mapped Variants
General Structure Information 3eg9 SEC24D crystal structure of the mammalian copii-coat protein sec23/24 bound to the transport signal sequence of membrin 3.0Å AUTH J.D.MANCIAS,J.GOLDBERGTITL STRUCTURAL BASIS OF CARGO MEMBRANE PROTEIN DISCRIMINATION BYTITL 2 THE HUMAN COPII COAT MACHINERY.REF EMBO J. V. 27 2918 2008REFN ISSN 0261-4189PMID 18843296DOI 10.1038/EMBOJ.2008.208 Variant Set Distributions Ripley’s K Analysis Plots […]
General Structure Information 2l0t STAM2 solution structure of the complex of ubiquitin and the vhs domain of stam2 -1.0Å AUTH A.LANGE,D.HOELLER,H.WIENK,O.MARCILLAT,J.M.LANCELIN,O.WALKERTITL NMR REVEALS A DIFFERENT MODE OF BINDING OF THE STAM2 VHSTITL 2 DOMAIN TO UBIQUITIN AND DIUBIQUITIN.REF BIOCHEMISTRY V. 50 48 2011REFN ISSN 0006-2960PMID 21121635DOI 10.1021/BI101594A Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 3f1i HGS human escrt-0 core complex 2.3Å AUTH X.REN,D.P.KLOER,Y.C.KIM,R.GHIRLANDO,L.F.SAIDI,G.HUMMER,AUTH 2 J.H.HURLEYTITL HYBRID STRUCTURAL MODEL OF THE COMPLETE HUMAN ESCRT-0TITL 2 COMPLEX.REF STRUCTURE V. 17 406 2009REFN ISSN 0969-2126PMID 19278655DOI 10.1016/J.STR.2009.01.012 Variant Set Distributions Mapped Variants