Assessment of Structural Intolerance and Durability
General Structure Information 3kq4 GIF structure of intrinsic factor-cobalamin bound to its receptor cubilin 3.3Å AUTH C.B.ANDERSEN,M.MADSEN,T.STORM,S.K.MOESTRUP,G.R.ANDERSENTITL STRUCTURAL BASIS FOR RECEPTOR RECOGNITION OFTITL 2 VITAMIN-B(12)-INTRINSIC FACTOR COMPLEXES.REF NATURE V. 464 445 2010REFN ISSN 0028-0836PMID 20237569DOI 10.1038/NATURE08874 Variant Set Distributions Mapped Variants
General Structure Information 1n6k RAB5A crystal structure of human rab5a a30p mutant complex with gdp and aluminum fluoride 1.55Å AUTH G.ZHU,J.LIU,S.TERZYAN,P.ZHAI,G.LI,X.C.ZHANGTITL HIGH RESOLUTION CRYSTAL STRUCTURES OF HUMAN RAB5ATITL 2 AND FIVE MUTANTS WITH SUBSTITUTIONS IN THETITL 3 CATALYTICALLY IMPORTANT PHOSPHATE-BINDING LOOPREF J.BIOL.CHEM. V. 278 2452 2003REFN ISSN 0021-9258PMID 12433916DOI 10.1074/JBC.M211042200 Variant Set Distributions Ripley’s K […]
General Structure Information 2bme RAB4A high resolution structure of gppnhp-bound human rab4a 1.57Å AUTH S.K.HUBER,A.J.SCHEIDIGTITL HIGH RESOLUTION CRYSTAL STRUCTURES OF HUMAN RAB4ATITL 2 IN ITS ACTIVE AND INACTIVE CONFORMATIONS.REF FEBS LETT. V. 579 2821 2005REFN ISSN 0014-5793PMID 15907487DOI 10.1016/J.FEBSLET.2005.04.020 Variant Set Distributions Mapped Variants
General Structure Information 3dz8 RAB3B crystal structure of human rab3b gtpase bound with gdp 1.9Å AUTH Y.SHEN,Y.TONG,D.SUKUMAR,W.TEMPEL,P.LOPPNAU,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,C.BOUNTRA,M.WILKSTROM,A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF HUMAN RAB3B GTPASE BOUND WITH GDPREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2h4m HNRNPA1 karyopherin beta2/transportin-m9nls 3.05Å AUTH B.J.LEE,A.E.CANSIZOGLU,T.H.LOUIS,Z.ZHANG,Y.M.CHOOKTITL RULES FOR NUCLEAR LOCALIZATION SEQUENCETITL 2 RECOGNITION BY KARYOPHERIN BETA 2.REF CELL(CAMBRIDGE,MASS.) V. 126 543 2006REFN ISSN 0092-8674PMID 16901787DOI 10.1016/J.CELL.2006.05.049 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2gf9 RAB3D crystal structure of human rab3d in complex with gdp 1.53Å AUTH B.HONG,J.WANG,L.SHEN,W.TEMPEL,R.LANDRY,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,M.SUNDSTROM,J.WEIGELT,AUTH 3 A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF HUMAN RAB3D IN COMPLEX WITHTITL 2 GDPREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2j3t TRAPPC6A the crystal structure of the bet3-trs33-bet5-trs23 complex. 2.4Å AUTH Y.KIM,S.RAUNSER,C.MUNGER,J.WAGNER,Y.SONG,M.CYGLER,T.WALZ,AUTH 2 B.OH,M.SACHERTITL THE ARCHITECTURE OF THE MULTISUBUNIT TRAPP I COMPLEXTITL 2 SUGGESTS A MODEL FOR VESICLE TETHERING.REF CELL(CAMBRIDGE,MASS.) V. 127 817 2006REFN ISSN 0092-8674PMID 17110339DOI 10.1016/J.CELL.2006.09.029 Variant Set Distributions Mapped Variants
General Structure Information 2cpt VPS4B solution structure of mit domain from human skd1 -1.0Å AUTH T.SUETAKE,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF MIT DOMAIN FROM HUMAN SKD1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2yps SNX3 crystal structure of the px domain of human sorting nexin 3 2.6Å AUTH P.CANNING,D.S.FROESE,T.KROJER,C.STRAIN-DAMERELL,F.VON DELFT,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,W.W.YUETITL CRYSTAL STRUCTURE OF THE PX DOMAIN OF HUMAN SORTING NEXIN 3REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2fau VPS26A crystal structure of human vps26 2.1Å AUTH H.SHI,R.ROJAS,J.S.BONIFACINO,J.H.HURLEYTITL THE RETROMER SUBUNIT VPS26 HAS AN ARRESTIN FOLD AND BINDSTITL 2 VPS35 THROUGH ITS C-TERMINAL DOMAIN.REF NAT.STRUCT.MOL.BIOL. V. 13 540 2006REFN ISSN 1545-9993PMID 16732284DOI 10.1038/NSMB1103 Variant Set Distributions Mapped Variants