Assessment of Structural Intolerance and Durability
General Structure Information 3q0q PUM2 crystal structure of the pumilio-homology domain from human pumilio2 in complex with p38alpha nrea 2.0Å AUTH G.LU,T.M.HALLTITL ALTERNATE MODES OF COGNATE RNA RECOGNITION BY HUMAN PUMILIOTITL 2 PROTEINS.REF STRUCTURE V. 19 361 2011REFN ISSN 0969-2126PMID 21397187DOI 10.1016/J.STR.2010.12.019 Variant Set Distributions Mapped Variants
General Structure Information 3q2t CPSF6 crystal structure of cfim68 rrm/cfim25/rna complex 3.06Å AUTH Q.YANG,M.COSENO,G.M.GILMARTIN,S.DOUBLIETITL CRYSTAL STRUCTURE OF A HUMAN CLEAVAGE FACTORTITL 2 CFI(M)25/CFI(M)68/RNA COMPLEX PROVIDES AN INSIGHT INTOTITL 3 POLY(A) SITE RECOGNITION AND RNA LOOPING.REF STRUCTURE V. 19 368 2011REFN ISSN 0969-2126PMID 21295486DOI 10.1016/J.STR.2010.12.021 Variant Set Distributions Mapped Variants
General Structure Information 3q0n PUM1 crystal structure of the pumilio-homology domain from human pumilio1 in complex with erk2 nre 2.4Å AUTH G.LU,T.M.HALLTITL ALTERNATE MODES OF COGNATE RNA RECOGNITION BY HUMAN PUMILIOTITL 2 PROTEINS.REF STRUCTURE V. 19 361 2011REFN ISSN 0969-2126PMID 21397187DOI 10.1016/J.STR.2010.12.019 Variant Set Distributions Mapped Variants
General Structure Information 3q0n PUM1 crystal structure of the pumilio-homology domain from human pumilio1 in complex with erk2 nre 2.4Å AUTH G.LU,T.M.HALLTITL ALTERNATE MODES OF COGNATE RNA RECOGNITION BY HUMAN PUMILIOTITL 2 PROTEINS.REF STRUCTURE V. 19 361 2011REFN ISSN 0969-2126PMID 21397187DOI 10.1016/J.STR.2010.12.019 Variant Set Distributions Mapped Variants
General Structure Information 3q0n PUM1 crystal structure of the pumilio-homology domain from human pumilio1 in complex with erk2 nre 2.4Å AUTH G.LU,T.M.HALLTITL ALTERNATE MODES OF COGNATE RNA RECOGNITION BY HUMAN PUMILIOTITL 2 PROTEINS.REF STRUCTURE V. 19 361 2011REFN ISSN 0969-2126PMID 21397187DOI 10.1016/J.STR.2010.12.019 Variant Set Distributions Mapped Variants
General Structure Information 4ed5 ELAVL1 crystal structure of the two n-terminal rrm domains of hur complexed with rna 2.0Å AUTH H.WANG,F.ZENG,Q.LIU,H.LIU,Z.LIU,L.NIU,M.TENG,X.LITITL THE STRUCTURE OF THE ARE-BINDING DOMAINS OF HU ANTIGEN RTITL 2 (HUR) UNDERGOES CONFORMATIONAL CHANGES DURING RNA BINDING.REF ACTA CRYSTALLOGR.,SECT.D V. 69 373 2013REFN ISSN 0907-4449PMID 23519412DOI 10.1107/S0907444912047828 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 2la5 FMR1 rna duplex-quadruplex junction complex with fmrp rgg peptide -1.0Å AUTH A.T.PHAN,V.KURYAVYI,J.C.DARNELL,A.SERGANOV,A.MAJUMDAR,AUTH 2 S.ILIN,T.RASLIN,A.POLONSKAIA,C.CHEN,D.CLAIN,R.B.DARNELL,AUTH 3 D.J.PATELTITL STRUCTURE-FUNCTION STUDIES OF FMRP RGG PEPTIDE RECOGNITIONTITL 2 OF AN RNA DUPLEX-QUADRUPLEX JUNCTION.REF NAT.STRUCT.MOL.BIOL. V. 18 796 2011REFN ISSN 1545-9993PMID 21642970DOI 10.1038/NSMB.2064 Variant Set Distributions Mapped Variants
General Structure Information 2leb SRSF2 solution structure of human srsf2 (sc35) rrm in complex with 5- uccagu-3 -1.0Å AUTH G.M.DAUBNER,A.CLERY,S.JAYNE,J.STEVENIN,F.H.ALLAINTITL A SYN-ANTI CONFORMATIONAL DIFFERENCE ALLOWS SRSF2 TOTITL 2 RECOGNIZE GUANINES AND CYTOSINES EQUALLY WELL.REF EMBO J. V. 31 162 2012REFN ISSN 0261-4189PMID 22002536DOI 10.1038/EMBOJ.2011.367 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic […]
General Structure Information 4hot IFIT5 crystal structure of full-length human ifit5 with 5`-triphosphate oligoadenine 2.5Å AUTH Y.M.ABBAS,A.PICHLMAIR,M.W.GORNA,G.SUPERTI-FURGA,B.NAGARTITL STRUCTURAL BASIS FOR VIRAL 5-PPP-RNA RECOGNITION BY HUMANTITL 2 IFIT PROTEINS.REF NATURE V. 494 60 2013REFN ISSN 0028-0836PMID 23334420DOI 10.1038/NATURE11783 Variant Set Distributions Mapped Variants
General Structure Information 3dpr VLDLR human rhinovirus 2 bound to a concatamer of the vldl receptor module v3 3.5Å AUTH J.QUEROL-AUDI,T.KONECSNI,J.POUS,O.CARUGO,I.FITA,N.VERDAGUER,AUTH 2 D.BLAASTITL MINOR GROUP HUMAN RHINOVIRUS-RECEPTOR INTERACTIONS: GEOMETRYTITL 2 OF MULTIMODULAR ATTACHMENT AND BASIS OF RECOGNITIONREF FEBS LETT. V. 583 235 2009REFN ISSN 0014-5793PMID 19073182DOI 10.1016/J.FEBSLET.2008.12.014 Variant Set Distributions Mapped Variants