2LEB.A | SRSF2

General Structure Information

PDB ID 2leb
HGNC Gene Label(s) SRSF2
Structure Name solution structure of human srsf2 (sc35) rrm in complex with 5- uccagu-3
Resolution -1.0Å
Reference AUTH G.M.DAUBNER,A.CLERY,S.JAYNE,J.STEVENIN,F.H.ALLAINTITL A SYN-ANTI CONFORMATIONAL DIFFERENCE ALLOWS SRSF2 TOTITL 2 RECOGNIZE GUANINES AND CYTOSINES EQUALLY WELL.REF EMBO J. V. 31 162 2012REFN ISSN 0261-4189PMID 22002536DOI 10.1038/EMBOJ.2011.367

Variant Set Distributions

ExAC Variants

Number Of Residues 101
Number Of SNVs 5
Number Of Permutations 239
Optimal Distance Threshold 7.0
K Statistic 0.2
p-value 0.365
COSMIC

Ripley’s K Analysis Plots

ExACCOSMIC

Variant Set Comparisons

Cosmic vs. ExAC

Pathogenic Proximity Analysis

COSMIC PathProx Analysis

Mapped Variants

[+] ExAC Missense Variants

[+] COSMIC Missense Variants