Assessment of Structural Intolerance and Durability
General Structure Information 2j76 EIF4B solution structure and rna interactions of the rna recognition motif from eukaryotic translation initiation factor 4b -1.0Å AUTH K.FLEMING,J.GHUMAN,X.M.YUAN,P.SIMPSON,A.SZENDROI,AUTH 2 S.MATTHEWS,S.CURRYTITL SOLUTION STRUCTURE AND RNA INTERACTIONS OF THE RNATITL 2 RECOGNITION MOTIF FROM EUKARYOTIC TRANSLATIONTITL 3 INITIATION FACTOR 4B.REF BIOCHEMISTRY V. 42 8966 2003REFN ISSN 0006-2960PMID 12885229DOI 10.1021/BI034506G Variant Set […]
General Structure Information 3hfv FARS2 crystal structure of human mitochondrial phenylalanyl-trna synthetase complexed with m-tyrosine 2.6Å AUTH L.KLIPCAN,N.MOOR,N.KESSLER,M.G.SAFROTITL EUKARYOTIC CYTOSOLIC AND MITOCHONDRIALTITL 2 PHENYLALANYL-TRNA SYNTHETASES CATALYZE THE CHARGINGTITL 3 OF TRNA WITH THE META-TYROSINEREF PROC.NATL.ACAD.SCI.USA V. 106 11045 2009REFN ISSN 0027-8424PMID 19549855DOI 10.1073/PNAS.0905212106 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3bpj EIF3J crystal structure of human translation initiation factor 3, subunit 1 alpha 1.85Å AUTH L.NEDYALKOVA,B.HONG,W.TEMPEL,F.MACKENZIE,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,J.WEIGELT,A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF HUMAN TRANSLATION INITIATION FACTOR 3,TITL 2 SUBUNIT 1 ALPHA.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2jgc EIF4E2 structure of the human eif4e homologous protein, 4ehp without ligand bound 2.4Å AUTH P.ROSETTANI,S.KNAPP,M.G.VISMARA,L.RUSCONI,AUTH 2 A.D.CAMERONTITL STRUCTURES OF THE HUMAN EIF4E HOMOLOGOUS PROTEIN,TITL 2 H4EHP, IN ITS M(7)GTP-BOUND AND UNLIGANDED FORMS.REF J.MOL.BIOL. V. 368 691 2007REFN ISSN 0022-2836PMID 17368478DOI 10.1016/J.JMB.2007.02.019 Variant Set Distributions Mapped Variants
General Structure Information 2uz8 EEF1E1 the crystal structure of p18, human translation elongation factor 1 epsilon 1 2.0Å AUTH K.J.KIM,M.C.PARK,S.J.CHOI,Y.S.OH,E.C.CHOI,H.J.CHO,AUTH 2 M.H.KIM,S.H.KIM,D.W.KIM,S.KIM,B.S.KANGTITL DETERMINATION OF THREE-DIMENSIONAL STRUCTURE ANDTITL 2 RESIDUES OF THE NOVEL TUMOR SUPPRESSOR AIMP3/P18TITL 3 REQUIRED FOR THE INTERACTION WITH ATM.REF J.BIOL.CHEM. V. 283 14032 2008REFN ISSN 0021-9258PMID 18343821DOI 10.1074/JBC.M800859200 Variant Set Distributions Mapped […]