Assessment of Structural Intolerance and Durability
General Structure Information 2i7t CPSF3 structure of human cpsf-73 2.1Å AUTH C.R.MANDEL,S.KANEKO,H.ZHANG,D.GEBAUER,V.VETHANTHAM,AUTH 2 J.L.MANLEY,L.TONGTITL POLYADENYLATION FACTOR CPSF-73 IS THE PRE-MRNATITL 2 3-END-PROCESSING ENDONUCLEASE.REF NATURE V. 444 953 2006REFN ISSN 0028-0836PMID 17128255DOI 10.1038/NATURE05363 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3gix TXNL4B crystal structure of human splicing factor dim2 1.33Å AUTH T.C.JIN,F.GUO,Y.T.WANG,A.HOWARD,Y.Z.ZHANGTITL CRYSTAL STRUCTURE OF HUMAN SPLICING FACTOR DIM2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3nnc CELF1 crystal structure of cugbp1 rrm1/2-rna complex 2.2Å AUTH M.TEPLOVA,J.SONG,H.Y.GAW,A.TEPLOV,D.J.PATELTITL STRUCTURAL INSIGHTS INTO RNA RECOGNITION BY THETITL 2 ALTERNATE-SPLICING REGULATOR CUG-BINDING PROTEIN 1.REF STRUCTURE V. 18 1364 2010REFN ISSN 0969-2126PMID 20947024DOI 10.1016/J.STR.2010.06.018 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3siu PRPF31 structure of a hprp31-15.5k-u4atac 5 stem loop complex, monomeric form 2.63Å AUTH S.LIU,H.GHALEI,R.LUHRMANN,M.C.WAHLTITL STRUCTURAL BASIS FOR THE DUAL U4 AND U4ATAC SNRNA-BINDINGTITL 2 SPECIFICITY OF SPLICEOSOMAL PROTEIN HPRP31.REF RNA V. 17 1655 2011REFN ISSN 1355-8382PMID 21784869DOI 10.1261/RNA.2690611 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3n9u CPSF7 crystal structure of the complex between the 25 kda subunit and the 59 kda subunit (rrm domain) of human cleavage factor im 1.92Å AUTH L.TRESAUGUES,M.WELIN,C.H.ARROWSMITH,H.BERGLUND,C.BOUNTRA,AUTH 2 R.COLLINS,A.M.EDWARDS,S.FLODIN,A.FLORES,S.GRASLUND,AUTH 3 M.HAMMARSTROM,I.JOHANSSON,T.KARLBERG,S.KOL,T.KOTENYOVA,AUTH 4 M.MOCHE,T.K.NIELSEN,T.NYMAN,C.PERSSON,H.SCHULER,P.SCHUTZ,AUTH 5 M.I.SIPONEN,A.G.THORSELL,S.VAN DER BERG,E.WAHLBERG,AUTH 6 J.WEIGELT,M.WISNIEWSKA,P.NORDLUNDTITL CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE 25 KDA SUBUNITTITL 2 AND THE […]