General Structure Information 3nbq UPP1 human uridine phosphorylase 1 (hupp1) with 5-fluorouracil 2.3Å AUTH T.P.ROOSILD,S.CASTRONOVOTITL ACTIVE SITE CONFORMATIONAL DYNAMICS IN HUMAN URIDINETITL 2 PHOSPHORYLASE 1.REF PLOS ONE V. 5 E1274 2010REFN ESSN 1932-6203PMID 20856879DOI 10.1371/JOURNAL.PONE.0012741 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1sd1 MTAP structure of human 5-deoxy-5-methylthioadenosine phosphorylase complexed with formycin a 2.03Å AUTH J.E.LEE,E.C.SETTEMBRE,K.A.CORNELL,M.K.RISCOE,J.R.SUFRIN,AUTH 2 S.E.EALICK,P.L.HOWELLTITL STRUCTURAL COMPARISON OF MTA PHOSPHORYLASE AND MTA/ADOHCYTITL 2 NUCLEOSIDASE EXPLAINS SUBSTRATE PREFERENCES AND IDENTIFIESTITL 3 REGIONS EXPLOITABLE FOR INHIBITOR DESIGN.REF BIOCHEMISTRY V. 43 5159 2004REFN ISSN 0006-2960PMID 15122881DOI 10.1021/BI035492H Variant Set Distributions Mapped Variants
General Structure Information 1sd1 MTAP structure of human 5-deoxy-5-methylthioadenosine phosphorylase complexed with formycin a 2.03Å AUTH J.E.LEE,E.C.SETTEMBRE,K.A.CORNELL,M.K.RISCOE,J.R.SUFRIN,AUTH 2 S.E.EALICK,P.L.HOWELLTITL STRUCTURAL COMPARISON OF MTA PHOSPHORYLASE AND MTA/ADOHCYTITL 2 NUCLEOSIDASE EXPLAINS SUBSTRATE PREFERENCES AND IDENTIFIESTITL 3 REGIONS EXPLOITABLE FOR INHIBITOR DESIGN.REF BIOCHEMISTRY V. 43 5159 2004REFN ISSN 0006-2960PMID 15122881DOI 10.1021/BI035492H Variant Set Distributions Mapped Variants
General Structure Information 1l5s PYGL human liver glycogen phosphorylase complexed with uric acid, n-acetyl- beta-d-glucopyranosylamine, and cp-403,700 2.1Å AUTH J.L.EKSTROM,T.A.PAULY,M.D.CARTY,W.C.SOELLER,J.CULP,AUTH 2 D.E.DANLEY,D.J.HOOVER,J.L.TREADWAY,E.M.GIBBS,R.J.FLETTERICK,AUTH 3 Y.S.DAY,D.G.MYSZKA,V.L.RATHTITL STRUCTURE-ACTIVITY ANALYSIS OF THE PURINE BINDING SITE OFTITL 2 HUMAN LIVER GLYCOGEN PHOSPHORYLASE.REF CHEM.BIOL. V. 9 915 2002REFN ISSN 1074-5521PMID 12204691DOI 10.1016/S1074-5521(02)00186-2 Variant Set Distributions Ripley’s K Analysis Plots Variant Set […]