Assessment of Structural Intolerance and Durability
General Structure Information 2yuy ARHGAP21 solution structure of pdz domain of rho gtpase activating protein 21 -1.0Å AUTH T.N.NIRAULA,M.YONEYAMA,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF PDZ DOMAIN OF RHO GTPASETITL 2 ACTIVATING PROTEIN 21REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3o46 MPP7 crystal structure of the pdz domain of mpp7 1.3Å AUTH L.NEDYALKOVA,Y.TONG,W.TEMPEL,N.ZHONG,X.GUAN,R.LANDRY,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,C.BOUNTRA,J.WEIGELT,A.BOCHKAREV,AUTH 3 H.PARKTITL CRYSTAL STRUCTURE OF THE PDZ DOMAIN OF MPP7REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1i16 IL16 structure of interleukin 16: implications for function, nmr, 20 structures -1.0Å AUTH P.MUHLHAHN,M.ZWECKSTETTER,J.GEORGESCU,C.CIOSTO,AUTH 2 C.RENNER,M.LANZENDORFER,K.LANG,D.AMBROSIUS,M.BAIER,AUTH 3 R.KURTH,T.A.HOLAKTITL STRUCTURE OF INTERLEUKIN 16 RESEMBLES A PDZ DOMAINTITL 2 WITH AN OCCLUDED PEPTIDE BINDING SITE.REF NAT.STRUCT.BIOL. V. 5 682 1998REFN ISSN 1072-8368PMID 9699630DOI 10.1038/1376 Variant Set Distributions Mapped Variants
General Structure Information 2he2 DLG2 crystal structure of the 3rd pdz domain of human discs large homologue 2, dlg2 1.5Å AUTH J.M.ELKINS,E.PAPAGRIGORIOU,G.BERRIDGE,X.YANG,AUTH 2 C.PHILLIPS,C.GILEADI,P.SAVITSKY,D.A.DOYLETITL STRUCTURE OF PICK1 AND OTHER PDZ DOMAINS OBTAINEDTITL 2 WITH THE HELP OF SELF-BINDING C-TERMINALTITL 3 EXTENSIONS.REF PROTEIN SCI. V. 16 683 2007REFN ISSN 0961-8368PMID 17384233DOI 10.1110/PS.062657507 Variant Set Distributions Mapped […]
General Structure Information 2byg DLG2 2nd pdz domain of discs large homologue 2 1.85Å AUTH J.M.ELKINS,E.PAPAGRIGORIOU,G.BERRIDGE,X.YANG,C.PHILLIPS,AUTH 2 C.GILEADI,C.SAVITSKY,D.A.DOYLETITL STRUCTURE OF PICK1 AND OTHER PDZ DOMAINS OBTAINED WITH THETITL 2 HELP OF SELF-BINDING C-TERMINAL EXTENSIONS.REF PROTEIN SCI. V. 16 683 2007REFN ISSN 0961-8368PMID 17384233DOI 10.1110/PS.062657507 Variant Set Distributions Mapped Variants
General Structure Information 1x6d IL16 solution structures of the pdz domain of human interleukin- 16 -1.0Å AUTH M.SATO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURES OF THE PDZ DOMAIN OF HUMANTITL 2 INTERLEUKIN-16REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2e7k MPP2 solution structure of the pdz domain from human maguk p55 subfamily member 2 -1.0Å AUTH X.R.QIN,C.KUROSAKI,M.YOSHIDA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PDZ DOMAIN FROM HUMANTITL 2 MAGUK P55 SUBFAMILY MEMBER 2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2e7k MPP2 solution structure of the pdz domain from human maguk p55 subfamily member 2 -1.0Å AUTH X.R.QIN,C.KUROSAKI,M.YOSHIDA,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE PDZ DOMAIN FROM HUMANTITL 2 MAGUK P55 SUBFAMILY MEMBER 2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3kzd TIAM1 crystal structure of free t-cell lymphoma invasion and metastasis-1 pdz domain 1.3Å AUTH T.R.SHEPHERD,S.M.KLAUS,X.LIU,S.RAMASWAMY,K.A.DEMALI,AUTH 2 E.J.FUENTESTITL THE TIAM1 PDZ DOMAIN COUPLES TO SYNDECAN1 AND PROMOTESTITL 2 CELL-MATRIX ADHESION.REF J.MOL.BIOL. V. 398 730 2010REFN ISSN 0022-2836PMID 20361982DOI 10.1016/J.JMB.2010.03.047 Variant Set Distributions Mapped Variants
General Structure Information 1u3b APBA1 auto-inhibition mechanism of x11s/mints family scaffold proteins revealed by the closed conformation of the tandem pdz domains -1.0Å AUTH J.-F.LONG,W.FENG,R.WANG,L.-N.CHAN,F.C.IP,J.XIA,AUTH 2 N.Y.IP,M.ZHANGTITL AUTOINHIBITION OF X11/MINT SCAFFOLD PROTEINSTITL 2 REVEALED BY THE CLOSED CONFORMATION OF THE PDZTITL 3 TANDEMREF NAT.STRUCT.MOL.BIOL. V. 12 722 2005REFN ISSN 1545-9993PMID 16007100DOI 10.1038/NSMB958 Variant Set Distributions […]