General Structure Information 3hkv PARP10 human poly(adp-ribose) polymerase 10, catalytic fragment in complex with an inhibitor 3-aminobenzamide 2.1Å AUTH T.KARLBERG,M.MOCHE,C.H.ARROWSMITH,H.BERGLUND,AUTH 2 C.BOUNTRA,R.COLLINS,A.M.EDWARDS,S.FLODIN,A.FLORES,AUTH 3 S.GRASLUND,M.HAMMARSTROM,A.JOHANSSON,I.JOHANSSON,AUTH 4 T.KOTENYOVA,A.KOTZSCH,T.K.NIELSEN,P.NORDLUND,AUTH 5 T.NYMAN,C.PERSSON,A.K.ROOS,J.SAGEMARK,P.SCHUTZ,AUTH 6 M.I.SIPONEN,A.G.THORSELL,L.TRESAUGUES,AUTH 7 S.VAN DEN BERG,J.WEIGELT,M.WELIN,M.WISNIEWSKA,AUTH 8 H.SCHULERTITL HUMAN POLY(ADP-RIBOSE) POLYMERASE 10, CATALYTICTITL 2 FRAGMENT IN COMPLEX WITH AN INHIBITORTITL 3 3-AMINOBENZAMIDEREF TO BE PUBLISHEDREFN Variant Set […]
General Structure Information 3blj PARP15 crystal structure of human poly(adp-ribose) polymerase 15, catalytic fragment 2.2Å AUTH T.KARLBERG,M.KLEPSCH,A.G.THORSELL,C.D.ANDERSSON,A.LINUSSON,AUTH 2 H.SCHULERTITL STRUCTURAL BASIS FOR LACK OF ADP-RIBOSYLTRANSFERASE ACTIVITYTITL 2 IN POLY(ADP-RIBOSE) POLYMERASE-13/ZINC FINGER ANTIVIRALTITL 3 PROTEIN.REF J.BIOL.CHEM. V. 290 7336 2015REFN ISSN 0021-9258PMID 25635049DOI 10.1074/JBC.M114.630160 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity […]
General Structure Information 4dqy PARP1 structure of human parp-1 bound to a dna double strand break 3.25Å AUTH M.F.LANGELIER,J.L.PLANCK,S.ROY,J.M.PASCALTITL STRUCTURAL BASIS FOR DNA DAMAGE-DEPENDENTTITL 2 POLY(ADP-RIBOSYL)ATION BY HUMAN PARP-1.REF SCIENCE V. 336 728 2012REFN ISSN 0036-8075PMID 22582261DOI 10.1126/SCIENCE.1216338 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2jvn PARP1 domain c of human parp-1 -1.0Å AUTH Z.TAO,P.GAO,D.W.HOFFMAN,H.W.LIUTITL DOMAIN C OF HUMAN POLY(ADP-RIBOSE) POLYMERASE-1 IS IMPORTANTTITL 2 FOR ENZYME ACTIVITY AND CONTAINS A NOVEL ZINC-RIBBON MOTIF.REF BIOCHEMISTRY V. 47 5804 2008REFN ISSN 0006-2960PMID 18452307DOI 10.1021/BI800018A Variant Set Distributions Mapped Variants