Assessment of Structural Intolerance and Durability
General Structure Information 1×51 MUTYH solution structure of the nudix domain from human a/g- specific adenine dna glycosylase alpha-3 splice isoform -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE NUDIX DOMAIN FROM HUMANTITL 2 A/G-SPECIFIC ADENINE DNA GLYCOSYLASE ALPHA-3TITL 3 SPLICE ISOFORMREF TO BE PUBLISHEDREFN Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3aca NUDT5 crystal structure of human nudt5 complexed with 8-oxo-dadp and manganese 2.05Å AUTH T.ARIMORI,H.TAMAOKI,T.NAKAMURA,H.KAMIYA,S.IKEMIZU,Y.TAKAGI,AUTH 2 T.ISHIBASHI,H.HARASHIMA,M.SEKIGUCHI,Y.YAMAGATATITL DIVERSE SUBSTRATE RECOGNITION AND HYDROLYSIS MECHANISMS OFTITL 2 HUMAN NUDT5REF NUCLEIC ACIDS RES. V. 39 8972 2011REFN ISSN 0305-1048PMID 21768126DOI 10.1093/NAR/GKR575 Variant Set Distributions Mapped Variants
General Structure Information 1q33 NUDT9 crystal structure of human adp-ribose pyrophosphatase nudt9 1.81Å AUTH B.W.SHEN,A.L.PERRAUD,A.SCHARENBERG,B.L.STODDARDTITL THE CRYSTAL STRUCTURE AND MUTATIONAL ANALYSIS OFTITL 2 HUMAN NUDT9REF J.MOL.BIOL. V. 332 385 2003REFN ISSN 0022-2836PMID 12948489DOI 10.1016/S0022-2836(03)00954-9 Variant Set Distributions Mapped Variants
General Structure Information 3kvh NUDT16L1 crystal structure of human protein syndesmos (nudt16-like protein) 1.7Å AUTH L.TRESAUGUES,M.I.SIPONEN,C.H.ARROWSMITH,H.BERGLUND,AUTH 2 C.BOUNTRA,R.COLLINS,A.M.EDWARDS,S.FLODIN,A.FLORES,AUTH 3 S.GRASLUND,M.HAMMARSTROM,A.JOHANSSON,I.JOHANSSON,A.KALLAS,AUTH 4 T.KARLBERG,T.KOTENYOVA,A.KOTZSCH,P.KRAULIS,M.MOCHE,AUTH 5 T.K.NIELSEN,T.NYMAN,C.PERSSON,A.K.ROOS,H.SCHULER,P.SCHUTZ,AUTH 6 A.G.THORSELL,S.VAN DEN BERG,J.WEIGELT,M.WELIN,M.WISNIEWSKA,AUTH 7 P.NORDLUNDTITL CRYSTAL STRUCTURE OF HUMAN PROTEIN SYNDESMOS (NUDT16L1)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3cou NUDT16 crystal structure of human nudix motif 16 (nudt16) 1.8Å AUTH L.TRESAUGUES,M.MOCHE,C.H.ARROWSMITH,H.BERGLUND,AUTH 2 R.D.BUSAM,R.COLLINS,L.G.DAHLGREN,A.M.EDWARDS,AUTH 3 S.FLODIN,A.FLORES,S.GRASLUND,M.HAMMARSTROM,AUTH 4 M.D.HERMAN,A.JOHANSSON,I.JOHANSSON,A.KALLAS,AUTH 5 T.KARLBERG,T.KOTENYOVA,L.LEHTIO,M.E.NILSSON,AUTH 6 T.NYMAN,C.PERSSON,J.SAGEMARK,H.SCHUELER,L.SVENSSON,AUTH 7 A.G.THORSELL,S.VAN DEN BERG,M.WELIN,J.WEIGELT,AUTH 8 M.WIKSTROM,P.NORDLUNDTITL CRYSTAL STRUCTURE OF HUMAN NUDIX MOTIF 16 (NUDT16).REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3mcf NUDT10 crystal structure of human diphosphoinositol polyphosphate phosphohydrolase 3-alpha 2.0Å AUTH L.TRESAUGUES,M.WELIN,C.H.ARROWSMITH,H.BERGLUND,AUTH 2 C.BOUNTRA,R.COLLINS,A.M.EDWARDS,S.FLODIN,A.FLORES,AUTH 3 S.GRASLUND,M.HAMMARSTROM,I.JOHANSSON,T.KARLBERG,AUTH 4 S.KOL,T.KOTENYOVA,M.MOCHE,T.NYMAN,C.PERSSON,AUTH 5 H.SCHULER,P.SCHUTZ,M.I.SIPONEN,A.G.THORSELL,AUTH 6 S.VAN DER BERG,E.WAHLBERG,J.WEIGELT,M.WISNIEWSKA,AUTH 7 P.NORDLUNDTITL CRYSTAL STRUCTURE OF HUMAN DIPHOSPHOINOSITOLTITL 2 POLYPHOSPHATE PHOSPHOHYDROLASE 3-ALPHAREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3n9u CPSF7 crystal structure of the complex between the 25 kda subunit and the 59 kda subunit (rrm domain) of human cleavage factor im 1.92Å AUTH L.TRESAUGUES,M.WELIN,C.H.ARROWSMITH,H.BERGLUND,C.BOUNTRA,AUTH 2 R.COLLINS,A.M.EDWARDS,S.FLODIN,A.FLORES,S.GRASLUND,AUTH 3 M.HAMMARSTROM,I.JOHANSSON,T.KARLBERG,S.KOL,T.KOTENYOVA,AUTH 4 M.MOCHE,T.K.NIELSEN,T.NYMAN,C.PERSSON,H.SCHULER,P.SCHUTZ,AUTH 5 M.I.SIPONEN,A.G.THORSELL,S.VAN DER BERG,E.WAHLBERG,AUTH 6 J.WEIGELT,M.WISNIEWSKA,P.NORDLUNDTITL CRYSTAL STRUCTURE OF THE COMPLEX BETWEEN THE 25 KDA SUBUNITTITL 2 AND THE […]
General Structure Information 3q2t CPSF6 crystal structure of cfim68 rrm/cfim25/rna complex 3.06Å AUTH Q.YANG,M.COSENO,G.M.GILMARTIN,S.DOUBLIETITL CRYSTAL STRUCTURE OF A HUMAN CLEAVAGE FACTORTITL 2 CFI(M)25/CFI(M)68/RNA COMPLEX PROVIDES AN INSIGHT INTOTITL 3 POLY(A) SITE RECOGNITION AND RNA LOOPING.REF STRUCTURE V. 19 368 2011REFN ISSN 0969-2126PMID 21295486DOI 10.1016/J.STR.2010.12.021 Variant Set Distributions Mapped Variants
General Structure Information 3h95 NUDT6 crystal structure of the nudix domain of nudt6 1.7Å AUTH L.TRESAUGUES,M.MOCHE,C.H.ARROWSMITH,H.BERGLUND,C.BOUNTRA,AUTH 2 R.COLLINS,A.M.EDWARDS,S.FLODIN,A.FLORES,S.GRASLUND,AUTH 3 M.HAMMARSTROM,A.JOHANSSON,I.JOHANSSON,T.KARLBERG,AUTH 4 T.KOTYENOVA,A.KOTZCH,T.K.NIELSEN,T.NYMAN,C.PERSSON,AUTH 5 J.SAGEMARK,H.SCHUELER,P.SCHUTZ,M.I.SIPONEN,L.SVENSSON,AUTH 6 A.G.THORSELL,S.VAN DEN BERG,J.WEIGELT,M.WELIN,M.WISNIEWSKA,AUTH 7 P.NORDLUNDTITL CRYSTAL STRUCTURE OF THE NUDIX DOMAIN OF NUDT6REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3fxt NUDT6 crystal structure of the n-terminal domain of human nudt6 2.3Å AUTH L.TRESAUGUES,M.WELIN,C.H.ARROWSMITH,H.BERGLUND,C.BOUNTRA,AUTH 2 R.COLLINS,L.G.DAHLGREN,A.M.EDWARDS,S.FLODIN,A.FLORES,AUTH 3 S.GRASLUND,M.HAMMARSTROM,A.JOHANSSON,I.JOHANSSON,T.KARLBERG,AUTH 4 T.KOTENYOVA,L.LEHTIO,M.MOCHE,M.E.NILSSON,T.NYMAN,C.PERSSON,AUTH 5 J.SAGEMARK,H.SCHUELER,M.I.SIPONEN,A.G.THORSELL,AUTH 6 S.VAN DEN BERG,J.WEIGELT,M.WIKSTROM,M.WISNIEWSKA,P.NORDLUNDTITL CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN NUDT6REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants