General Structure Information 2uvq UCK1 crystal structure of human uridine-cytidine kinase 1 in complex with adp 3.0Å AUTH U.KOSINSKA,P.STENMARK,C.ARROWSMITH,H.BERGLUND,R.BUSAM,AUTH 2 R.COLLINS,A.EDWARDS,U.B.ERICSSON,S.FLODIN,A.FLORES,AUTH 3 S.GRASLUND,M.HAMMARSTROM,B.M.HALLBERG,L.HOLMBERG SCHIAVONE,AUTH 4 M.HOGBOM,I.JOHANSSON,T.KARLBERG,T.KOTENYOVA,M.MOCHE,AUTH 5 M.E.P.NILSSON,T.NYMAN,D.OGG,C.PERSSON,J.SAGEMARK,AUTH 6 M.SUNDSTROM,J.UPPENBERG,M.UPPSTEN,A.G.THORSELL,AUTH 7 S.VAN DEN BERG,J.WEIGELT,M.WELIN,P.NORDLUNDTITL STRUCTURE OF HUMAN URIDINE-CYTIDINE KINASE 1REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3nbq UPP1 human uridine phosphorylase 1 (hupp1) with 5-fluorouracil 2.3Å AUTH T.P.ROOSILD,S.CASTRONOVOTITL ACTIVE SITE CONFORMATIONAL DYNAMICS IN HUMAN URIDINETITL 2 PHOSPHORYLASE 1.REF PLOS ONE V. 5 E1274 2010REFN ESSN 1932-6203PMID 20856879DOI 10.1371/JOURNAL.PONE.0012741 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1sd1 MTAP structure of human 5-deoxy-5-methylthioadenosine phosphorylase complexed with formycin a 2.03Å AUTH J.E.LEE,E.C.SETTEMBRE,K.A.CORNELL,M.K.RISCOE,J.R.SUFRIN,AUTH 2 S.E.EALICK,P.L.HOWELLTITL STRUCTURAL COMPARISON OF MTA PHOSPHORYLASE AND MTA/ADOHCYTITL 2 NUCLEOSIDASE EXPLAINS SUBSTRATE PREFERENCES AND IDENTIFIESTITL 3 REGIONS EXPLOITABLE FOR INHIBITOR DESIGN.REF BIOCHEMISTRY V. 43 5159 2004REFN ISSN 0006-2960PMID 15122881DOI 10.1021/BI035492H Variant Set Distributions Mapped Variants
General Structure Information 1sd1 MTAP structure of human 5-deoxy-5-methylthioadenosine phosphorylase complexed with formycin a 2.03Å AUTH J.E.LEE,E.C.SETTEMBRE,K.A.CORNELL,M.K.RISCOE,J.R.SUFRIN,AUTH 2 S.E.EALICK,P.L.HOWELLTITL STRUCTURAL COMPARISON OF MTA PHOSPHORYLASE AND MTA/ADOHCYTITL 2 NUCLEOSIDASE EXPLAINS SUBSTRATE PREFERENCES AND IDENTIFIESTITL 3 REGIONS EXPLOITABLE FOR INHIBITOR DESIGN.REF BIOCHEMISTRY V. 43 5159 2004REFN ISSN 0006-2960PMID 15122881DOI 10.1021/BI035492H Variant Set Distributions Mapped Variants
General Structure Information 3ldl HSPA5 crystal structure of human grp78 (70kda heat shock protein 5 / bip) atpase domain in complex with atp 2.3Å AUTH A.T.MACIAS,D.S.WILLIAMSON,N.ALLEN,J.BORGOGNONI,A.CLAY,AUTH 2 Z.DANIELS,P.DOKURNO,M.J.DRYSDALE,G.L.FRANCIS,C.J.GRAHAM,AUTH 3 R.HOWES,N.MATASSOVA,J.B.MURRAY,R.PARSONS,T.SHAW,AUTH 4 A.E.SURGENOR,L.TERRY,Y.WANG,M.WOOD,A.J.MASSEYTITL ADENOSINE-DERIVED INHIBITORS OF 78 KDA GLUCOSE REGULATEDTITL 2 PROTEIN (GRP78) ATPASE: INSIGHTS INTO ISOFORM SELECTIVITY.REF J.MED.CHEM. V. 54 4034 2011REFN ISSN 0022-2623PMID 21526763DOI […]