Assessment of Structural Intolerance and Durability
General Structure Information 4c9b CWC22 crystal structure of eif4aiii-cwc22 complex 2.0Å AUTH G.BUCHWALD,S.SCHUESSLER,C.BASQUIN,H.LE HIR,E.CONTITITL CRYSTAL STRUCTURE OF THE HUMAN EIF4AIII-CWC22 COMPLEX SHOWSTITL 2 HOW A DEAD-BOX PROTEIN IS INHIBITED BY A MIF4G DOMAINREF PROC.NATL.ACAD.SCI.USA V. 110 E4611 2013REFN ISSN 0027-8424PMID 24218557DOI 10.1073/PNAS.1314684110 Variant Set Distributions Mapped Variants
General Structure Information 1uw4 UPF2 the structural basis of the interaction between nonsense mediated decay factors upf2 and upf3 1.95Å AUTH J.KADLEC,E.IZAURRALDE,S.CUSACKTITL THE STRUCTURAL BASIS FOR THE INTERACTION BETWEENTITL 2 NONSENSE-MEDIATED MRNA DECAY FACTORS UPF2 AND UPF3REF NAT.STRUCT.MOL.BIOL. V. 11 330 2004REFN ISSN 1545-9993PMID 15004547DOI 10.1038/NSMB741 Variant Set Distributions Mapped Variants
General Structure Information 1uw4 UPF3B the structural basis of the interaction between nonsense mediated decay factors upf2 and upf3 1.95Å AUTH J.KADLEC,E.IZAURRALDE,S.CUSACKTITL THE STRUCTURAL BASIS FOR THE INTERACTION BETWEENTITL 2 NONSENSE-MEDIATED MRNA DECAY FACTORS UPF2 AND UPF3REF NAT.STRUCT.MOL.BIOL. V. 11 330 2004REFN ISSN 1545-9993PMID 15004547DOI 10.1038/NSMB741 Variant Set Distributions Mapped Variants
General Structure Information 2hwx SMG6 structure of human smg6 e1282c pin domain mutant. 1.9Å AUTH F.GLAVAN,I.BEHM-ANSMANT,E.IZAURRALDE,E.CONTITITL STRUCTURES OF THE PIN DOMAINS OF SMG6 AND SMG5TITL 2 REVEAL A NUCLEASE WITHIN THE MRNA SURVEILLANCETITL 3 COMPLEX.REF EMBO J. V. 25 5117 2006REFN ISSN 0261-4189PMID 17053788DOI 10.1038/SJ.EMBOJ.7601377 Variant Set Distributions Mapped Variants
General Structure Information 4a8x RNPS1 structure of the core asap complex 1.9Å AUTH A.G.MURACHELLI,J.EBERT,C.BASQUIN,H.LE HIR,E.CONTITITL THE STRUCTURE OF THE ASAP CORE COMPLEX REVEALS THETITL 2 EXISTENCE OF A PININ-CONTAINING PSAP COMPLEXREF NAT.STRUCT.MOL.BIOL. V. 19 378 2012REFN ISSN 1545-9993PMID 22388736DOI 10.1038/NSMB.2242 Variant Set Distributions Mapped Variants
General Structure Information 4c9b EIF4A3 crystal structure of eif4aiii-cwc22 complex 2.0Å AUTH G.BUCHWALD,S.SCHUESSLER,C.BASQUIN,H.LE HIR,E.CONTITITL CRYSTAL STRUCTURE OF THE HUMAN EIF4AIII-CWC22 COMPLEX SHOWSTITL 2 HOW A DEAD-BOX PROTEIN IS INHIBITED BY A MIF4G DOMAINREF PROC.NATL.ACAD.SCI.USA V. 110 E4611 2013REFN ISSN 0027-8424PMID 24218557DOI 10.1073/PNAS.1314684110 Variant Set Distributions Mapped Variants