2HWX.A | SMG6

General Structure Information

PDB ID 2hwx
HGNC Gene Label(s) SMG6
Structure Name structure of human smg6 e1282c pin domain mutant.
Resolution 1.9Å
Reference AUTH F.GLAVAN,I.BEHM-ANSMANT,E.IZAURRALDE,E.CONTITITL STRUCTURES OF THE PIN DOMAINS OF SMG6 AND SMG5TITL 2 REVEAL A NUCLEASE WITHIN THE MRNA SURVEILLANCETITL 3 COMPLEX.REF EMBO J. V. 25 5117 2006REFN ISSN 0261-4189PMID 17053788DOI 10.1038/SJ.EMBOJ.7601377

Variant Set Distributions

ExAC Variants

Number Of Residues 165
Number Of SNVs 39
Number Of Permutations 24158
Optimal Distance Threshold 9.0
K Statistic 0.047
p-value 0.137

Mapped Variants

[+] ExAC Missense Variants