Assessment of Structural Intolerance and Durability
General Structure Information 2l2d OTUD7A solution nmr structure of human uba-like domain of otud7a_11_83, nesg target ht6304a/ocsp target otud7a_11_83/sgc-toronto -1.0Å AUTH B.WU,A.ASINAS,A.YEE,R.DOHERTY,A.LEMAK,A.GUTMANAS,AUTH 2 S.HOULISTON,A.SEMESI,C.H.ARROWSMITH,G.T.MONTELIONE,AUTH 3 S.DHE-PAGANONTITL THE AMINO-TERMINAL UBA DOMAIN OF OTUD7AREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4l7e HDDC2 three dimensional structure of mutant d78a of human hd domain- containing protein 2, genomics consortium (nesg) target hr6723 2.23Å AUTH A.KUZIN,M.SU,A..YAKUNIN,N.BELOGLAZOVA,J.SEETHARAMAN,AUTH 2 M.MAGLAQUI,R.XIAO,D.LEE,G.BROWN,R.FLICK,J.K.EVERETT,AUTH 3 T.B.ACTON,G.T.MONTELIONE,J.F.HUNT,L.TONG,AUTH 4 NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG)TITL NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET HR6723REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]
General Structure Information 1mi1 NBEA crystal structure of the ph-beach domain of human neurobeachin 2.9Å AUTH G.JOGL,Y.SHEN,D.GEBAUER,J.LI,K.WIEGMANN,H.KASHKAR,AUTH 2 M.KRONKE,L.TONGTITL CRYSTAL STRUCTURE OF THE BEACH DOMAIN REVEALS ANTITL 2 UNUSUAL FOLD AND EXTENSIVE ASSOCIATION WITH ATITL 3 NOVEL PH DOMAIN.REF EMBO J. V. 21 4785 2002REFN ISSN 0261-4189PMID 12234919DOI 10.1093/EMBOJ/CDF502 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 2l0b PJA1 solution nmr structure of zinc finger domain of e3 ubiquitin-protein ligase praja-1 from homo sapiens, northeast structural genomics consortium (nesg) target hr4710b -1.0Å AUTH G.LIU,S.TONG,R.XIAO,T.B.ACTON,J.K.EVERETT,G.T.MONTELIONETITL SOLUTION STRUCTURE OF ZINC FINGER DOMAIN OF E3TITL 2 UBIQUITIN-PROTEIN LIGASE PROTEIN PRAJA-1 FROM HOMO SAPIENS,TITL 3 NORTHEAST STRUCTURAL GENOMICS CONSORTIUM (NESG) TARGETTITL 4 HR4710BREF […]
General Structure Information 2jxx NFATC2IP nmr solution structure of ubiquitin-like domain of nfatc2ip. northeast structural genomics consortium target hr5627 -1.0Å AUTH R.S.DOHERTY,S.DHE-PAGANON,C.FARES,A.LEMAK,C.BUTLER,AUTH 2 S.SRISAILAM,M.KARRA,A.YEE,J.WEIGELT,A.M.EDWARDS,AUTH 3 C.H.ARROWSMITHTITL SOLUTION STRUCTURE OF UBIQUITIN-LIKE DOMAIN OFTITL 2 NFATC2IP.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3syx SPRED1 crystal structure of the wh1 domain from human sprouty-related, evh1 domain-containing protein. northeast structural genomics consortium target hr5538b. 2.45Å AUTH S.VOROBIEV,M.SU,J.SEETHARAMAN,S.SAHDEV,R.XIAO,C.CICCOSANTI,AUTH 2 R.SHASTRY,J.K.EVERETT,R.NAIR,T.B.ACTON,B.ROST,AUTH 3 G.T.MONTELIONE,L.TONG,J.F.HUNTTITL CRYSTAL STRUCTURE OF THE WH1 DOMAIN FROM HUMANTITL 2 SPROUTY-RELATED, EVH1 DOMAIN-CONTAINING PROTEIN.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2l76 NFATC2IP solution nmr structure of human nfatc2ip ubiquitin-like domain, nfatc2ip_244_338, nesg target ht65a/ocsp target hs00387_244_338/sgc- toronto -1.0Å AUTH R.DOHERTY,B.WU,A.YEE,A.LEMAK,S.HOULISTON,C.FARES,S.SRISALAM,AUTH 2 C.BULTER,A.M.EDWARDS,J.WEIGELT,S.DHE-PAGANON,C.H.ARROWSMITHTITL HUMAN NFATC2IP UBIQUITIN-LIKE DOMAINSREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3mqp BCL2A1 crystal structure of human bfl-1 in complex with noxa bh3 peptide, northeast structural genomics consortium target hr2930 2.24Å AUTH R.GUAN,R.XIAO,L.ZHAO,T.B.ACTON,C.GELINAS,G.T.MONTELIONETITL CRYSTAL STRUCTURE OF HUMAN BFL-1 IN COMPLEX WITH NOXA BH3TITL 2 PEPTIDEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 2oq0 IFI16 crystal structure of the first hin-200 domain of interferon-inducible protein 16 2.0Å AUTH J.C.C.LIAO,R.LAM,M.RAVICHANDRAN,J.MA,W.TEMPEL,N.Y.CHIRGADZE,AUTH 2 C.H.ARROWSMITHTITL CRYSTAL STRUCTURE OF THE FIRST HIN-200 DOMAIN OFTITL 2 INTERFERON-INDUCIBLE PROTEIN 16REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3b6y IFI16 crystal structure of the second hin-200 domain of interferon-inducible protein 16 2.35Å AUTH J.C.C.LIAO,R.LAM,M.RAVICHANDRAN,S.DUAN,W.TEMPEL,AUTH 2 N.Y.CHIRGADZE,C.H.ARROWSMITHTITL CRYSTAL STRUCTURE ANALYSIS OF THE SECOND HIN DOMAIN OFTITL 2 IFI16.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants