General Structure Information
| PDB ID | 3mqp |
| HGNC Gene Label(s) | BCL2A1 |
| Structure Name | crystal structure of human bfl-1 in complex with noxa bh3 peptide, northeast structural genomics consortium target hr2930 |
| Resolution | 2.24Å |
| Reference | AUTH R.GUAN,R.XIAO,L.ZHAO,T.B.ACTON,C.GELINAS,G.T.MONTELIONETITL CRYSTAL STRUCTURE OF HUMAN BFL-1 IN COMPLEX WITH NOXA BH3TITL 2 PEPTIDEREF TO BE PUBLISHEDREFN |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 150 |
| Number Of SNVs | 35 |
| Number Of Permutations | 9843 |
| Optimal Distance Threshold | 6.0 |
| K Statistic | 0.015 |
| p-value | 0.213 |
COSMIC
| Number Of Residues | 150 |
| Number Of SNVs | 5 |
| Number Of Permutations | 1205 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.1 |
| p-value | 0.239 |
Ripley’s K Analysis Plots
ExACCOSMIC


Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 35 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 20.0 |
| K Statistic | -0.233 |
| p-value | 0.632 |