Assessment of Structural Intolerance and Durability
General Structure Information 4aj5 SKA2 crystal structure of the ska core complex 3.32Å AUTH A.A.JEYAPRAKASH,A.SANTAMARIA,U.JAYACHANDRAN,Y.W.CHAN,AUTH 2 C.BENDA,E.A.NIGG,E.CONTITITL STRUCTURAL AND FUNCTIONAL ORGANIZATION OF THE SKA COMPLEX,TITL 2 A KEY COMPONENT OF THE KINETOCHORE-MICROTUBULE INTERFACE.REF MOL.CELL V. 46 274 2012REFN ISSN 1097-2765PMID 22483620DOI 10.1016/J.MOLCEL.2012.03.005 Variant Set Distributions Mapped Variants
General Structure Information 2v14 KIF16B kinesin 16b phox-homology domain (kif16b) 2.2Å AUTH N.R.BLATNER,M.I.WILSON,C.LEI,W.HONG,D.MURRAY,AUTH 2 R.L.WILLIAMS,W.CHOTITL THE STRUCTURAL BASIS OF NOVEL ENDOSOME ANCHORINGTITL 2 ACTIVITY OF KIF16B KINESIN.REF EMBO J. V. 26 3709 2007REFN ISSN 0261-4189PMID 17641687DOI 10.1038/SJ.EMBOJ.7601800 Variant Set Distributions Mapped Variants
General Structure Information 2cp0 CLIP3 solution structure of the 1st cap-gly domain in human clip- 170-related protein clipr59 -1.0Å AUTH K.SAITO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 1ST CAP-GLY DOMAIN INTITL 2 HUMAN CLIP-170-RELATED PROTEIN CLIPR59REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 4aj5 SKA3 crystal structure of the ska core complex 3.32Å AUTH A.A.JEYAPRAKASH,A.SANTAMARIA,U.JAYACHANDRAN,Y.W.CHAN,AUTH 2 C.BENDA,E.A.NIGG,E.CONTITITL STRUCTURAL AND FUNCTIONAL ORGANIZATION OF THE SKA COMPLEX,TITL 2 A KEY COMPONENT OF THE KINETOCHORE-MICROTUBULE INTERFACE.REF MOL.CELL V. 46 274 2012REFN ISSN 1097-2765PMID 22483620DOI 10.1016/J.MOLCEL.2012.03.005 Variant Set Distributions Mapped Variants
General Structure Information 4k92 CLASP1 a cryptic tog domain with a distinct architecture underlies clasp- dependent bipolar spindle formation 2.0Å AUTH J.B.LEANO,S.L.ROGERS,K.C.SLEPTITL A CRYPTIC TOG DOMAIN WITH A DISTINCT ARCHITECTURE UNDERLIESTITL 2 CLASP-DEPENDENT BIPOLAR SPINDLE FORMATION.REF STRUCTURE V. 21 939 2013REFN ISSN 0969-2126PMID 23727231DOI 10.1016/J.STR.2013.04.018 Variant Set Distributions Mapped Variants
General Structure Information 3lre KIF18A crystal structure analysis of human kinesin-8 motor domain 2.2Å AUTH C.PETERS,K.BREJC,L.BELMONT,A.J.BODEY,Y.LEE,M.YU,J.GUO,AUTH 2 R.SAKOWICZ,J.HARTMAN,C.A.MOORESTITL INSIGHT INTO THE MOLECULAR MECHANISM OF THE MULTITASKINGTITL 2 KINESIN-8 MOTOR.REF EMBO J. V. 29 3437 2010REFN ISSN 0261-4189PMID 20818331DOI 10.1038/EMBOJ.2010.220 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2coz CEP350 solution structure of the cap-gly domain in human centrosome-associated protein cap350 -1.0Å AUTH K.SAITO,S.KOSHIBA,M.INOUE,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE CAP-GLY DOMAIN IN HUMANTITL 2 CENTROSOME-ASSOCIATED PROTEIN CAP350REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2yuh TBCC solution structure of the c-terminal region in human tubulin folding cofactor c -1.0Å AUTH K.SAITO,N.TOCHIO,T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE C-TERMINAL REGION INTITL 2 HUMAN TUBULIN FOLDING COFACTOR CREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2r8u MAPRE1 structure of fragment of human end-binding protein 1 (eb1) containing the n-terminal domain at 1.35 a resolution 1.35Å AUTH X.HUANG,L.L.LOVELACE,D.SMITH,L.LEBIODATITL STRUCTURE OF FRAGMENT OF HUMAN END-BINDING PROTEINTITL 2 1 (EB1) CONTAINING THE N-TERMINAL DOMAIN AT 1.35 ATITL 3 RESOLUTIONREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3bfn KIF22 crystal structure of the motor domain of human kinesin family member 22 2.3Å AUTH H.ZHU,Y.SHEN,W.TEMPEL,E.DOBROVETSKY,F.MACKENZIE,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,J.WEIGELT,A.BOCHKAREV,H.PARKTITL CRYSTAL STRUCTURE OF THE MOTOR DOMAIN OF HUMAN KINESINTITL 2 FAMILY MEMBER 22.REF TO BE PUBLISHEDREFN Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants