General Structure Information 3ewf HDAC8 crystal structure analysis of human hdac8 h143a variant complexed with substrate. 2.5Å AUTH D.P.DOWLING,S.L.GANTT,S.G.GATTIS,C.A.FIERKE,AUTH 2 D.W.CHRISTIANSONTITL STRUCTURAL STUDIES OF HUMAN HISTONE DEACETYLASE 8TITL 2 AND ITS SITE-SPECIFIC VARIANTS COMPLEXED WITHTITL 3 SUBSTRATE AND INHIBITORS.REF BIOCHEMISTRY V. 47 13554 2008REFN ISSN 0006-2960PMID 19053282DOI 10.1021/BI801610C Variant Set Distributions Pathogenic Proximity Analysis Mapped […]
General Structure Information 1nud TGM3 role of calcium ions in the activation and activity of the transglutaminase 3 enzyme (3 calciums, active form) 2.7Å AUTH B.AHVAZI,K.M.BOESHANS,W.IDLER,U.BAXA,P.M.STEINERTTITL ROLES OF CALCIUM IONS IN THE ACTIVATION ANDTITL 2 ACTIVITY OF THE TRANSGLUTAMINASE 3 ENZYMEREF J.BIOL.CHEM. V. 278 23834 2003REFN ISSN 0021-9258PMID 12679341DOI 10.1074/JBC.M301162200 Variant Set Distributions Ripley’s K […]
General Structure Information 1nud TGM3 role of calcium ions in the activation and activity of the transglutaminase 3 enzyme (3 calciums, active form) 2.7Å AUTH B.AHVAZI,K.M.BOESHANS,W.IDLER,U.BAXA,P.M.STEINERTTITL ROLES OF CALCIUM IONS IN THE ACTIVATION ANDTITL 2 ACTIVITY OF THE TRANSGLUTAMINASE 3 ENZYMEREF J.BIOL.CHEM. V. 278 23834 2003REFN ISSN 0021-9258PMID 12679341DOI 10.1074/JBC.M301162200 Variant Set Distributions Ripley’s K […]
General Structure Information 4ie2 ARG2 crystal structure of human arginase-2 complexed with inhibitor 1h 2.21Å AUTH A.GOLEBIOWSKI,R.PAUL BECKETT,M.VAN ZANDT,M.K.JI,AUTH 2 D.WHITEHOUSE,T.R.RYDER,E.JAGDMANN,M.ANDREOLI,A.MAZUR,AUTH 3 M.PADMANILAYAM,A.COUSIDO-SIAH,A.MITSCHLER,F.X.RUIZ,AUTH 4 A.PODJARNY,H.SCHROETERTITL 2-SUBSTITUTED-2-AMINO-6-BORONOHEXANOIC ACIDS AS ARGINASETITL 2 INHIBITORS.REF BIOORG.MED.CHEM.LETT. V. 23 2027 2013REFN ISSN 0960-894XPMID 23453840DOI 10.1016/J.BMCL.2013.02.024 Variant Set Distributions Mapped Variants
General Structure Information 2qnk HAAO crystal structure of human 3-hydroxyanthranilate 3,4-dioxygenase 1.6Å AUTH E.BITTO,C.A.BINGMAN,G.E.WESENBERG,G.N.PHILLIPS JR.TITL CRYSTAL STRUCTURE OF HUMAN 3-HYDROXYANTHRANILATETITL 2 3,4-DIOXYGENASE.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3cki TIMP3 crystal structure of the tace-n-timp-3 complex 2.3Å AUTH M.WISNIEWSKA,P.GOETTIG,K.MASKOS,E.BELOUSKI,AUTH 2 D.WINTERS,R.HECHT,R.BLACK,W.BODETITL STRUCTURAL DETERMINANTS OF THE ADAM INHIBITION BYTITL 2 TIMP-3: CRYSTAL STRUCTURE OF THE TACE-N-TIMP-3TITL 3 COMPLEX.REF J.MOL.BIOL. V. 381 1307 2008REFN ISSN 0022-2836PMID 18638486DOI 10.1016/J.JMB.2008.06.088 Variant Set Distributions Mapped Variants
General Structure Information 4c6f CAD crystal structure of the dihydroorotase domain of human cad bound to substrate at ph 6.5 1.26Å AUTH A.GRANDE-GARCIA,N.LALLOUS,C.DIAZ-TEJADA,S.RAMON-MAIQUESTITL STRUCTURE, FUNCTIONAL CHARACTERIZATION AND EVOLUTION OF THETITL 2 DIHYDROOROTASE DOMAIN OF HUMAN CAD.REF STRUCTURE V. 22 185 2014REFN ISSN 0969-2126PMID 24332717DOI 10.1016/J.STR.2013.10.016 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons […]