Assessment of Structural Intolerance and Durability
General Structure Information 2lg1 AKAP13 solution structure of the human akap13 ph domain and stabilizing dh helix -1.0Å AUTH M.LENOIR,M.SUGAWARA,J.KAUR,L.J.BALL,M.OVERDUINTITL STRUCTURAL INSIGHTS INTO THE ACTIVATION OF THE RHOA GTPASETITL 2 BY THE LBC ONCOPROTEIN.REF J.BIOL.CHEM. V. 3 215 2014REFN ISSN 0021-9258PMID 24993829DOI 10.1074/JBC.M114.561787 Variant Set Distributions Mapped Variants
General Structure Information 2odd RUNX1T1 solution structure of the mynd domain from aml1-eto complexed with smrt, a corepressor -1.0Å AUTH Y.LIU,W.CHEN,J.GAUDET,M.D.CHENEY,L.ROUDAIA,AUTH 2 T.CIERPICKI,R.C.KLET,K.HARTMAN,T.M.LAUE,N.A.SPECK,AUTH 3 J.H.BUSHWELLERTITL STRUCTURAL BASIS FOR RECOGNITION OF SMRT/N-COR BYTITL 2 THE MYND DOMAIN AND ITS CONTRIBUTION TO AML1/ETOSTITL 3 ACTIVITY.REF CANCER CELL V. 11 483 2007REFN ISSN 1535-6108PMID 17560331DOI 10.1016/J.CCR.2007.04.010 Variant Set […]
General Structure Information 3sh5 HSPG2 calcium-bound laminin g like domain 3 from human perlecan 2.8Å AUTH B.VAN LE,H.KIM,J.CHOI,J.H.KIM,M.J.HAHN,C.LEE,K.K.KIM,AUTH 2 H.Y.HWANGTITL CRYSTAL STRUCTURE OF THE LG3 DOMAIN OF ENDOREPELLIN, ANTITL 2 ANGIOGENESIS INHIBITOR.REF J.MOL.BIOL. V. 414 231 2011REFN ISSN 0022-2836PMID 21996443DOI 10.1016/J.JMB.2011.09.048 Variant Set Distributions Mapped Variants
General Structure Information 2odd RUNX1T1 solution structure of the mynd domain from aml1-eto complexed with smrt, a corepressor -1.0Å AUTH Y.LIU,W.CHEN,J.GAUDET,M.D.CHENEY,L.ROUDAIA,AUTH 2 T.CIERPICKI,R.C.KLET,K.HARTMAN,T.M.LAUE,N.A.SPECK,AUTH 3 J.H.BUSHWELLERTITL STRUCTURAL BASIS FOR RECOGNITION OF SMRT/N-COR BYTITL 2 THE MYND DOMAIN AND ITS CONTRIBUTION TO AML1/ETOSTITL 3 ACTIVITY.REF CANCER CELL V. 11 483 2007REFN ISSN 1535-6108PMID 17560331DOI 10.1016/J.CCR.2007.04.010 Variant Set […]
General Structure Information 3sh5 HSPG2 calcium-bound laminin g like domain 3 from human perlecan 2.8Å AUTH B.VAN LE,H.KIM,J.CHOI,J.H.KIM,M.J.HAHN,C.LEE,K.K.KIM,AUTH 2 H.Y.HWANGTITL CRYSTAL STRUCTURE OF THE LG3 DOMAIN OF ENDOREPELLIN, ANTITL 2 ANGIOGENESIS INHIBITOR.REF J.MOL.BIOL. V. 414 231 2011REFN ISSN 0022-2836PMID 21996443DOI 10.1016/J.JMB.2011.09.048 Variant Set Distributions Mapped Variants
General Structure Information 1rly GTF2B rdc-derived models of the zinc ribbon domain of human general transcription tfiib (zinc bound structures) -1.0Å AUTH M.GHOSH,L.M.ELSBY,T.K.MAL,J.M.GOODING,S.G.ROBERTS,AUTH 2 M.IKURATITL PROBING ZN2+-BINDING EFFECTS ON THE ZINC-RIBBONTITL 2 DOMAIN OF HUMAN GENERAL TRANSCRIPTION FACTOR TFIIB.REF BIOCHEM.J. V. 378 317 2004REFN ISSN 0264-6021PMID 14641108DOI 10.1042/BJ20031706 Variant Set Distributions Mapped Variants
General Structure Information 2wcb S100A12 s100a12 complex with zinc in the absence of calcium 1.73Å AUTH O.V.MOROZ,E.V.BLAGOVA,A.J.WILKINSON,K.S.WILSON,I.B.BRONSTEINTITL THE CRYSTAL STRUCTURES OF HUMAN S100A12 IN APO FORM AND INTITL 2 COMPLEX WITH ZINC: NEW INSIGHTS INTO S100A12TITL 3 OLIGOMERISATION.REF J.MOL.BIOL. V. 391 536 2009REFN ISSN 0022-2836PMID 19501594DOI 10.1016/J.JMB.2009.06.004 Variant Set Distributions Mapped Variants
General Structure Information 4kfm GNB1 crystal structure of the g protein-gated inward rectifier k+ channel girk2 (kir3.2) in complex with the beta-gamma g protein subunits 3.45Å AUTH M.R.WHORTON,R.MACKINNONTITL X-RAY STRUCTURE OF THE MAMMALIAN GIRK2-BETA GAMMA G-PROTEINTITL 2 COMPLEX.REF NATURE V. 498 190 2013REFN ISSN 0028-0836PMID 23739333DOI 10.1038/NATURE12241 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 4kfm GNG2 crystal structure of the g protein-gated inward rectifier k+ channel girk2 (kir3.2) in complex with the beta-gamma g protein subunits 3.45Å AUTH M.R.WHORTON,R.MACKINNONTITL X-RAY STRUCTURE OF THE MAMMALIAN GIRK2-BETA GAMMA G-PROTEINTITL 2 COMPLEX.REF NATURE V. 498 190 2013REFN ISSN 0028-0836PMID 23739333DOI 10.1038/NATURE12241 Variant Set Distributions Mapped Variants
General Structure Information 2kwo HIST4H4 solution structure of the double phd (plant homeodomain) fingers of human transcriptional protein dpf3b bound to a histone h4 peptide containing n-terminal acetylation at serine 1 -1.0Å AUTH L.ZENG,Q.ZHANG,S.LI,A.N.PLOTNIKOV,M.J.WALSH,M.M.ZHOUTITL MECHANISM AND REGULATION OF ACETYLATED HISTONE BINDING BYTITL 2 THE TANDEM PHD FINGER OF DPF3B.REF NATURE V. 466 258 2010REFN ISSN […]