General Structure Information 3km0 HSD17B1 17betahsd1 in complex with 3beta-diol 2.3Å AUTH M.MAZUMDAR,J.CHEN,S.-X.LINTITL MOLECULAR BASIS OF SEX-STEROID TRANSLATIONREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3bg3 PC crystal structure of human pyruvate carboxylase (missing the biotin carboxylase domain at the n-terminus) 2.8Å AUTH S.XIANG,L.TONGTITL CRYSTAL STRUCTURES OF HUMAN AND STAPHYLOCOCCUSTITL 2 AUREUS PYRUVATE CARBOXYLASE AND MOLECULAR INSIGHTSTITL 3 INTO THE CARBOXYLTRANSFER REACTION.REF NAT.STRUCT.MOL.BIOL. V. 15 295 2008REFN ISSN 1545-9993PMID 18297087DOI 10.1038/NSMB.1393 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 3ccz HMGCR thermodynamic and structure guided design of statin hmg-coa reductase inhibitors 1.7Å AUTH R.W.SARVER,E.BILLS,G.BOLTON,L.D.BRATTON,AUTH 2 N.L.CASPERS,J.B.DUNBAR,M.S.HARRIS,R.H.HUTCHINGS,AUTH 3 R.M.KENNEDY,S.D.LARSEN,A.PAVLOVSKY,J.A.PFEFFERKORN,AUTH 4 G.BAINBRIDGETITL THERMODYNAMIC AND STRUCTURE GUIDED DESIGN OFTITL 2 STATIN BASED INHIBITORS OFTITL 3 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE.REF J.MED.CHEM. V. 51 3804 2008REFN ISSN 0022-2623PMID 18540668DOI 10.1021/JM7015057 Variant Set Distributions Mapped Variants
General Structure Information 2f15 PRKAB2 glycogen-binding domain of the amp-activated protein kinase beta2 subunit 2.0Å AUTH J.R.WALKER,L.WYBENGA-GROOT,P.J.FINERTY JR.,AUTH 2 E.NEWMAN,F.M.MACKENZIE,J.WEIGELT,M.SUNDSTROM,AUTH 3 C.ARROWSMITH,A.EDWARDS,A.BOCHKAREV,S.DHE-PAGANONTITL STRUCTURE OF THE GLYCOGEN-BINDING DOMAIN OF THETITL 2 AMP-ACTIVATED PROTEIN KINASE BETA2 SUBUNITREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3kxo HPGDS an orally active inhibitor bound at the active site of hpgds 2.1Å AUTH C.P.CARRON,J.I.TRUJILLO,K.L.OLSON,W.HUANG,B.C.HAMPER,T.DICE,AUTH 2 B.E.NEAL,M.J.PELC,J.DAY,D.C.ROHRER,J.R.KIEFER,J.B.MOON,AUTH 3 B.A.SCHWEITZER,T.D.BLAKE,S.R.TURNER,R.WOERNDLE,B.L.CASE,AUTH 4 C.P.BONO,V.M.DILWORTH,C.L.FUNCKES-SHIPPY,B.L.HOOD,AUTH 5 G.M.JEROME,C.M.KORNMEIER,M.R.RADABAUGH,M.L.WILLIAMS,AUTH 6 M.S.DAVIES,C.D.WEGNER,D.J.WELSCH,W.M.ABRAHAM,C.J.WARREN,AUTH 7 M.E.DOWTY,F.HUA,A.ZUTSHI,J.Z.YANG,A.THORARENSENTITL DISCOVERY OF AN ORAL POTENT SELECTIVE INHIBITOR OFTITL 2 HEMATOPOIETIC PROSTAGLANDIN D SYNTHASEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 3gid ACACB the biotin carboxylase (bc) domain of human acetyl-coa carboxylase 2 (acc2) in complex with soraphen a 2.3Å AUTH B.RAYMER,M.KAVANA,A.PRICE,B.WANG,L.CORCORAN,R.KULATHILA,AUTH 2 J.GROARKE,T.MANNTITL SYNTHESIS AND CHARACTERIZATION OF A BODIPY-LABELEDTITL 2 DERIVATIVE OF SORAPHEN A THAT BINDS TO ACETYL-COATITL 3 CARBOXYLASE.REF BIOORG.MED.CHEM.LETT. V. 19 2804 2009REFN ISSN 0960-894XPMID 19359168DOI 10.1016/J.BMCL.2009.03.107 Variant Set Distributions […]