Assessment of Structural Intolerance and Durability
General Structure Information 3kq4 GIF structure of intrinsic factor-cobalamin bound to its receptor cubilin 3.3Å AUTH C.B.ANDERSEN,M.MADSEN,T.STORM,S.K.MOESTRUP,G.R.ANDERSENTITL STRUCTURAL BASIS FOR RECEPTOR RECOGNITION OFTITL 2 VITAMIN-B(12)-INTRINSIC FACTOR COMPLEXES.REF NATURE V. 464 445 2010REFN ISSN 0028-0836PMID 20237569DOI 10.1038/NATURE08874 Variant Set Distributions Mapped Variants
General Structure Information 2vig ACADS crystal structure of human short-chain acyl coa dehydrogenase 1.9Å AUTH A.C.W.PIKE,N.PANTIC,E.PARIZOTTO,O.GILEADI,AUTH 2 E.UGOCHUKWU,F.VON DELFT,J.WEIGELT,C.H.ARROWSMITH,AUTH 3 A.EDWARDS,U.OPPERMANNTITL CRYSTAL STRUCTURE OF HUMAN SHORT-CHAIN ACYL COATITL 2 DEHYDROGENASEREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3bqq PSAP crystal structure of human saposin d (triclinic) 2.0Å AUTH K.POPOVIC,G.G.PRIVETITL STRUCTURES OF THE HUMAN CERAMIDE ACTIVATOR PROTEINTITL 2 SAPOSIN D.REF ACTA CRYSTALLOGR.,SECT.D V. 64 589 2008REFN ISSN 0907-4449PMID 18453694DOI 10.1107/S0907444908003120 Variant Set Distributions Mapped Variants
General Structure Information 3gxm GBA crystal structure of acid-beta-glucosidase at ph 4.5, phosphate crystallization condition 2.2Å AUTH R.L.LIEBERMAN,J.A.DAQUINO,D.RINGE,G.A.PETSKOTITL EFFECTS OF PH AND IMINOSUGAR PHARMACOLOGICAL CHAPERONES ONTITL 2 LYSOSOMAL GLYCOSIDASE STRUCTURE AND STABILITY.REF BIOCHEMISTRY V. 48 4816 2009REFN ISSN 0006-2960PMID 19374450DOI 10.1021/BI9002265 Variant Set Distributions Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3kq4 CUBN structure of intrinsic factor-cobalamin bound to its receptor cubilin 3.3Å AUTH C.B.ANDERSEN,M.MADSEN,T.STORM,S.K.MOESTRUP,G.R.ANDERSENTITL STRUCTURAL BASIS FOR RECEPTOR RECOGNITION OFTITL 2 VITAMIN-B(12)-INTRINSIC FACTOR COMPLEXES.REF NATURE V. 464 445 2010REFN ISSN 0028-0836PMID 20237569DOI 10.1038/NATURE08874 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants