Assessment of Structural Intolerance and Durability
General Structure Information 1yo8 THBS2 structure of the c-terminal domain of human thrombospondin-2 2.6Å AUTH C.B.CARLSON,D.A.BERNSTEIN,D.S.ANNIS,T.M.MISENHEIMER,AUTH 2 B.L.HANNAH,D.F.MOSHER,J.L.KECKTITL STRUCTURE OF THE CALCIUM-RICH SIGNATURE DOMAIN OF HUMANTITL 2 THROMBOSPONDIN-2REF NAT.STRUCT.MOL.BIOL. V. 12 910 2005REFN ISSN 1545-9993PMID 16186819DOI 10.1038/NSMB997 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3pos CALR crystal structure of the globular domain of human calreticulin 1.65Å AUTH A.CHOUQUET,H.PAIDASSI,W.L.LING,P.FRACHET,G.HOUEN,G.J.ARLAUD,AUTH 2 C.GABORIAUDTITL X-RAY STRUCTURE OF THE HUMAN CALRETICULIN GLOBULAR DOMAINTITL 2 REVEALS A PEPTIDE-BINDING AREA AND SUGGESTS ATITL 3 MULTI-MOLECULAR MECHANISMREF PLOS ONE V. 6 E1788 2011REFN ESSN 1932-6203PMID 21423620DOI 10.1371/JOURNAL.PONE.0017886 Variant Set Distributions Mapped Variants
General Structure Information 3ici PPIB crystal structure of cyclophilin b in complex with calmegin fragment 1.7Å AUTH G.KOZLOV,S.BASTOS-ARISTIZABAL,P.MAATTANEN,A.ROSENAUER,AUTH 2 F.ZHENG,A.KILLIKELLY,J.F.TREMPE,D.Y.THOMAS,K.GEHRINGTITL STRUCTURAL BASIS OF CYCLOPHILIN B BINDING BY THETITL 2 CALNEXIN/CALRETICULIN P-DOMAIN.REF J.BIOL.CHEM. V. 285 35551 2010REFN ISSN 0021-9258PMID 20801878DOI 10.1074/JBC.M110.160101 Variant Set Distributions Mapped Variants
General Structure Information 1uuh CD44 hyaluronan binding domain of human cd44 2.2Å AUTH P.TERIETE,S.BANERJI,M.NOBLE,C.BLUNDELL,A.WRIGHT,AUTH 2 A.PICKFORD,E.LOWE,D.MAHONEY,M.TAMMI,J.KAHMANN,AUTH 3 I.CAMPBELL,A.DAY,D.JACKSONTITL STRUCTURE OF THE REGULATORY HYALURONAN-BINDINGTITL 2 DOMAIN IN THE INFLAMMATORY LEUKOCYTE HOMINGTITL 3 RECEPTOR CD44REF MOL.CELL V. 13 483 2004REFN ISSN 1097-2765PMID 14992719DOI 10.1016/S1097-2765(04)00080-2 Variant Set Distributions Mapped Variants
General Structure Information 1g1q SELP crystal structure of p-selectin lectin/egf domains 2.4Å AUTH W.S.SOMERS,J.TANG,G.D.SHAW,R.T.CAMPHAUSENTITL INSIGHTS INTO THE MOLECULAR BASIS OF LEUKOCYTETITL 2 TETHERING AND ROLLING REVEALED BY STRUCTURES OF P-TITL 3 AND E-SELECTIN BOUND TO SLE(X) AND PSGL-1.REF CELL(CAMBRIDGE,MASS.) V. 103 467 2000REFN ISSN 0092-8674PMID 11081633DOI 10.1016/S0092-8674(00)00138-0 Variant Set Distributions Ripley’s K Analysis Plots Variant […]
General Structure Information 3cfw SELL l-selectin lectin and egf domains 2.2Å AUTH P.MEHTA,R.P.MCEVERTITL STRUCTURE OF LECTIN AND EGF DOMAINS OF L-SELECTINREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1gzw LGALS1 x-ray crystal structure of human galectin-1 1.7Å AUTH M.I.F.LOPEZ-LUCENDO,D.SOLIS,S.ANDRE,J.HIRABAYASHI,AUTH 2 K.KASAI,H.KALTNER,H.J.GABIUS,A.ROMEROTITL GROWTH-REGULATORY HUMAN GALECTIN-1:TITL 2 CRYSTALLOGRAPHIC CHARACTERISATION OF THETITL 3 STRUCTURAL CHANGES INDUCED BY SINGLE-SITETITL 4 MUTATIONS AND THEIR IMPACT ON THE THERMODYNAMICSTITL 5 OF LIGAND BINDINGREF J.MOL.BIOL. V. 343 957 2004REFN ISSN 0022-2836PMID 15476813DOI 10.1016/J.JMB.2004.08.078 Variant Set Distributions Mapped […]
General Structure Information 2w08 APCS the structure of serum amyloid p component bound to 0- phospho-threonine 1.7Å AUTH S.E.KOLSTOE,B.H.RIDHA,V.BELLOTTI,N.WANG,AUTH 2 C.V.ROBINSON,S.J.CRUTCH,G.KEIR,R.KUKKASTENVEHMAS,AUTH 3 J.R.GALLIMORE,W.L.HUTCHINSON,P.N.HAWKINS,S.P.WOOD,AUTH 4 M.N.ROSSOR,M.B.PEPYSTITL MOLECULAR DISSECTION OF ALZHEIMERS DISEASETITL 2 NEUROPATHOLOGY BY DEPLETION OF SERUM AMYLOID PTITL 3 COMPONENT.REF PROC.NATL.ACAD.SCI.USA V. 106 7619 2009REFN ISSN 0027-8424PMID 19372378DOI 10.1073/PNAS.0902640106 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 1hlc LGALS2 x-ray crystal structure of the human dimeric s-lac lectin, l-14-ii, in complex with lactose at 2.9 angstroms resolution 2.9Å AUTH Y.D.LOBSANOV,M.A.GITT,H.LEFFLER,S.H.BARONDES,AUTH 2 J.M.RINITITL X-RAY CRYSTAL STRUCTURE OF THE HUMAN DIMERIC S-LACTITL 2 LECTIN, L-14-II, IN COMPLEX WITH LACTOSE AT 2.9-ATITL 3 RESOLUTION.REF J.BIOL.CHEM. V. 268 27034 1993REFN ISSN 0021-9258PMID 8262940 […]
General Structure Information 2j60 FCN3 h-ficolin complexed to d-fucose 1.8Å AUTH V.GARLATTI,N.BELLOY,L.MARTIN,M.LACROIX,AUTH 2 M.MATSUSHITA,Y.ENDO,T.FUJITA,J.C.FONTECILLA-CAMPS,AUTH 3 G.J.ARLAUD,N.M.THIELENS,C.GABORIAUDTITL STRUCTURAL INSIGHTS INTO THE INNATE IMMUNETITL 2 RECOGNITION SPECIFICITIES OF L- AND H-FICOLINS.REF EMBO J. V. 26 623 2007REFN ISSN 0261-4189PMID 17215869DOI 10.1038/SJ.EMBOJ.7601500 Variant Set Distributions Mapped Variants