General Structure Information 3gcw PCSK9 pcsk9:egfa(h306y) 2.7Å AUTH M.C.MCNUTT,H.J.KWON,C.CHEN,J.R.CHEN,J.D.HORTON,T.A.LAGACETITL ANTAGONISM OF SECRETED PCSK9 INCREASES LOW DENSITYTITL 2 LIPOPROTEIN RECEPTOR EXPRESSION IN HEPG2 CELLS.REF J.BIOL.CHEM. V. 284 10561 2009REFN ISSN 0021-9258PMID 19224862DOI 10.1074/JBC.M808802200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3gcx PCSK9 pcsk9:egfa (ph 7.4) 2.7Å AUTH M.C.MCNUTT,H.J.KWON,C.CHEN,J.R.CHEN,J.D.HORTON,T.A.LAGACETITL ANTAGONISM OF SECRETED PCSK9 INCREASES LOW DENSITYTITL 2 LIPOPROTEIN RECEPTOR EXPRESSION IN HEPG2 CELLS.REF J.BIOL.CHEM. V. 284 10561 2009REFN ISSN 0021-9258PMID 19224862DOI 10.1074/JBC.M808802200 Variant Set Distributions Mapped Variants
General Structure Information 2m0p LRP2 solution structure of the tenth complement type repeat of human megalin -1.0Å AUTH R.DAGIL,C.OSHEA,A.NYKJAR,A.M.BONVIN,B.B.KRAGELUNDTITL GENTAMICIN BINDS TO THE MEGALIN RECEPTOR AS A COMPETITIVETITL 2 INHIBITOR USING THE COMMON LIGAND BINDING MOTIF OFTITL 3 COMPLEMENT TYPE REPEATS: INSIGHT FROM THE NMR STRUCTURE OFTITL 4 THE 10TH COMPLEMENT TYPE REPEAT DOMAIN ALONE […]
General Structure Information 2m0p LRP2 solution structure of the tenth complement type repeat of human megalin -1.0Å AUTH R.DAGIL,C.OSHEA,A.NYKJAR,A.M.BONVIN,B.B.KRAGELUNDTITL GENTAMICIN BINDS TO THE MEGALIN RECEPTOR AS A COMPETITIVETITL 2 INHIBITOR USING THE COMMON LIGAND BINDING MOTIF OFTITL 3 COMPLEMENT TYPE REPEATS: INSIGHT FROM THE NMR STRUCTURE OFTITL 4 THE 10TH COMPLEMENT TYPE REPEAT DOMAIN ALONE […]
General Structure Information 1n7d LDLR extracellular domain of the ldl receptor 3.7Å AUTH G.RUDENKO,L.HENRY,K.HENDERSON,K.ICHTCHENKO,M.S.BROWN,AUTH 2 J.L.GOLDSTEIN,J.DEISENHOFERTITL STRUCTURE OF THE LDL RECEPTOR EXTRACELLULAR DOMAIN ATTITL 2 ENDOSOMAL PHREF SCIENCE V. 298 2353 2002REFN ISSN 0036-8075PMID 12459547DOI 10.1126/SCIENCE.1078124 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants