Assessment of Structural Intolerance and Durability
General Structure Information 1nbq F11R crystal structure of human junctional adhesion molecule type 1 2.9Å AUTH A.E.PROTA,J.A.CAMPBELL,P.SCHELLING,J.C.FORREST,AUTH 2 M.J.WATSON,T.R.PETERS,M.AURRAND-LIONS,B.A.IMHOF,AUTH 3 T.S.DERMODY,T.STEHLETITL CRYSTAL STRUCTURE OF HUMAN JUNCTIONAL ADHESIONTITL 2 MOLECULE 1: IMPLICATIONS FOR REOVIRUS BINDINGREF PROC.NATL.ACAD.SCI.USA V. 100 5366 2003REFN ISSN 0027-8424PMID 12697893DOI 10.1073/PNAS.0937718100 Variant Set Distributions Mapped Variants
General Structure Information 2osg TJP2 solution structure and binding property of the domain- swapped dimer of zo2pdz2 -1.0Å AUTH J.W.WU,Y.S.YANG,J.H.ZHANG,P.JI,W.J.DU,P.JIANG,AUTH 2 D.H.XIE,H.D.HUANG,M.WU,G.Z.ZHANG,J.H.WU,Y.Y.SHITITL DOMAIN-SWAPPED DIMERIZATION OF THE SECOND PDZTITL 2 DOMAIN OF ZO2 MAY PROVIDE A STRUCTURAL BASIS FORTITL 3 THE POLYMERIZATION OF CLAUDINSREF J.BIOL.CHEM. V. 282 35988 2007REFN ISSN 0021-9258PMID 17897942DOI 10.1074/JBC.M703826200 Variant Set Distributions […]
General Structure Information 4cgy RMI1 crystal structure of the human topoisomerase iii alpha-rmi1 complex 2.85Å AUTH N.BOCQUET,A.H.BIZARD,W.ABDULRAHMAN,N.B.LARSEN,M.FATY,AUTH 2 S.CAVADINI,R.D.BUNKER,S.C.KOWALCZYKOWSKI,P.CEJKA,AUTH 3 I.D.HICKSON,N.H.THOMATITL STRUCTURAL AND MECHANISTIC INSIGHT INTO HOLLIDAY-JUNCTIONTITL 2 DISSOLUTION BY TOPOISOMERASE IIIALPHA AND RMI1REF NAT.STRUCT.MOL.BIOL. V. 21 261 2014REFN ISSN 1545-9993PMID 24509834DOI 10.1038/NSMB.2775 Variant Set Distributions Mapped Variants
General Structure Information 3bpu MAGI1 crystal structure of the 3rd pdz domain of human membrane associated guanylate kinase, c677s and c709s double mutant 1.6Å AUTH E.S.PILKA,V.HOZJAN,C.COOPER,A.C.W.PIKE,J.ELKINS,D.A.DOYLE,AUTH 2 F.VON DELFT,C.H.ARROWSMITH,A.M.EDWARDS,J.WEIGELT,U.OPPERMANNTITL CRYSTAL STRUCTURE OF THE 3RD PDZ DOMAIN OF HUMAN MEMBRANETITL 2 ASSOCIATED GUANYLATE KINASE, C677S AND C709S DOUBLE MUTANT.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped […]
General Structure Information 2kpk MAGI1 magi-1 pdz1 -1.0Å AUTH S.CHARBONNIER,Y.NOMINE,J.RAMIREZ,K.LUCK,A.CHAPELLE,AUTH 2 R.H.STOTE,G.TRAVE,B.KIEFFER,R.A.ATKINSONTITL THE STRUCTURAL AND DYNAMIC RESPONSE OF MAGI-1 PDZ1 WITHTITL 2 NON-CANONICAL DOMAIN BOUNDARIES TO BINDING OF HUMANTITL 3 PAPILLOMAVIRUS (HPV) E6REF J.MOL.BIOL. 2011REFN ESSN 1089-8638PMID 21238461DOI 10.1016/J.JMB.2011.01.015 Variant Set Distributions Mapped Variants
General Structure Information 2r4h MAGI1 crystal structure of a c1190s mutant of the 6th pdz domain of human membrane associated guanylate kinase 2.05Å AUTH E.UGOCHUKWU,E.S.PILKA,V.HOZJAN,K.L.KAVANAGH,C.COOPER,AUTH 2 A.C.W.PIKE,J.M.ELKINS,D.A.DOYLE,F.VON DELFT,M.SUNDSTROM,AUTH 3 C.H.ARROWSMITH,J.WEIGELT,A.M.EDWARDS,U.OPPERMANNTITL CRYSTAL STRUCTURE OF A C1190S MUTANT OF THE 6TH PDZ DOMAINTITL 2 OF HUMAN MEMBRANE ASSOCIATED GUANYLATE KINASE.REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s […]
General Structure Information 3ff7 KLRG1 structure of nk cell receptor klrg1 bound to e-cadherin 1.8Å AUTH Y.LI,M.HOFMANN,Q.WANG,L.TENG,L.K.CHLEWICKI,AUTH 2 H.PIRCHER,R.A.MARIUZZATITL STRUCTURE OF NATURAL KILLER CELL RECEPTOR KLRG1TITL 2 BOUND TO E-CADHERIN REVEALS BASIS FORTITL 3 MHC-INDEPENDENT MISSING SELF RECOGNITION.REF IMMUNITY V. 31 35 2009REFN ISSN 1074-7613PMID 19604491DOI 10.1016/J.IMMUNI.2009.04.019 Variant Set Distributions Mapped Variants
General Structure Information 2db5 INADL solution structure of the first pdz domain of inad-like protein -1.0Å AUTH K.INOUE,C.KUROSAKI,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST PDZ DOMAIN OFTITL 2 INAD-LIKE PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2ehr INADL solution structure of the sixth pdz domain of human inad- like protein -1.0Å AUTH K.INOUE,F.HAYASHI,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SIXTH PDZ DOMAIN OFTITL 2 HUMAN INAD-LIKE PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2kiv ANKS1B aida-1 sam domain tandem -1.0Å AUTH A.KURABI,S.BRENER,M.MOBLI,J.J.KWAN,L.W.DONALDSONTITL A NUCLEAR LOCALIZATION SIGNAL AT THE SAM-SAM DOMAINTITL 2 INTERFACE OF AIDA-1 SUGGESTS A REQUIREMENT FORTITL 3 DOMAIN UNCOUPLING PRIOR TO NUCLEAR IMPORT.REF J.MOL.BIOL. V. 392 1168 2009REFN ISSN 0022-2836PMID 19666031DOI 10.1016/J.JMB.2009.08.004 Variant Set Distributions Mapped Variants