Assessment of Structural Intolerance and Durability
General Structure Information 3e4c CASP1 procaspase-1 zymogen domain crystal strucutre 2.05Å AUTH J.M.ELLIOTT,L.ROUGE,C.WIESMANN,J.M.SCHEERTITL CRYSTAL STRUCTURE OF PROCASPASE-1 ZYMOGEN DOMAIN REVEALSTITL 2 INSIGHT INTO INFLAMMATORY CASPASE AUTOACTIVATIONREF J.BIOL.CHEM. V. 284 6546 2009REFN ISSN 0021-9258PMID 19117953DOI 10.1074/JBC.M806121200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3qwr IL12B crystal structure of il-23 in complex with an adnectin 3.25Å AUTH V.RAMAMURTHY,S.R.KRYSTEK,A.BUSH,A.WEI,S.L.EMANUEL,AUTH 2 R.DAS GUPTA,A.JANJUA,L.CHENG,M.MURDOCK,B.ABRAMCZYK,D.COHEN,AUTH 3 Z.LIN,P.MORIN,J.H.DAVIS,M.DABRITZ,D.C.MCLAUGHLIN,K.A.RUSSO,AUTH 4 G.CHAO,M.C.WRIGHT,V.A.JENNY,L.J.ENGLE,E.FURFINE,S.SHERIFFTITL STRUCTURES OF ADNECTIN/PROTEIN COMPLEXES REVEAL AN EXPANDEDTITL 2 BINDING FOOTPRINT.REF STRUCTURE V. 20 259 2012REFN ISSN 0969-2126PMID 22325775DOI 10.1016/J.STR.2011.11.016 Variant Set Distributions Mapped Variants