Assessment of Structural Intolerance and Durability
General Structure Information 2epa KLF10 solution structure of the first and second zf-c2h2 domains from human krueppel-like factor 10 -1.0Å AUTH K.IZUMI,F.HAYASHI,M.YOSHIDA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST AND SECOND ZF-C2H2TITL 2 DOMAINS FROM HUMAN KRUEPPEL-LIKE FACTOR 10REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1x4g TIAL1 solution structure of rrm domain in nucleolysin tiar -1.0Å AUTH F.HE,Y.MUTO,M.INOUE,T.KIGAWA,M.SHIROUZU,T.TERADA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF RRM DOMAIN IN NUCLEOLYSINTITL 2 TIARREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 1b22 RAD51 rad51 (n-terminal domain) -1.0Å AUTH H.AIHARA,Y.ITO,H.KURUMIZAKA,S.YOKOYAMA,T.SHIBATATITL THE N-TERMINAL DOMAIN OF THE HUMAN RAD51 PROTEINTITL 2 BINDS DNA: STRUCTURE AND A DNA BINDING SURFACE ASTITL 3 REVEALED BY NMR.REF J.MOL.BIOL. V. 290 495 1999REFN ISSN 0022-2836PMID 10390347DOI 10.1006/JMBI.1999.2904 Variant Set Distributions Mapped Variants
General Structure Information 2dbj MERTK solution structures of the fn3 domain of human proto- oncogene tyrosine-protein kinase mer precursor -1.0Å AUTH M.SATO,N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURES OF THE FN3 DOMAIN OF HUMANTITL 2 PROTO-ONCOGENE TYROSINE-PROTEIN KINASE MERTITL 3 PRECURSORREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis […]
General Structure Information 2rs9 BRPF1 solution structure of the bromodomain of human brpf1 in complex with histone h4k5ac peptide -1.0Å AUTH X.QIN,F.HAYASHI,S.YOKOYAMATITL SITE-SPECIFIC HISTONE RECOGNITION BY THE BROMODOMAIN OFTITL 2 BRPF1 AND THE ROLE IN MOZ/MORF HISTONE ACETYLTRANSFERASETITL 3 COMPLEXESREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2yuz MYBPC1 solution structure of 4th immunoglobulin domain of slow type myosin-binding protein c -1.0Å AUTH T.N.NIRAULA,N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF 4TH IMMUNOGLOBULIN DOMAIN OFTITL 2 SLOW TYPE MYOSIN-BINDING PROTEIN CREF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 1wz0 SUMO2 solution structure of human sumo-2 (smt3b), a ubiquitin- like protein -1.0Å AUTH C.ZHAO,K.SAITO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF HUMAN SUMO-2 (SMT3B), ATITL 2 UBIQUITIN-LIKE PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3oe8 CXCR4 crystal structure of the cxcr4 chemokine receptor in complex with a small molecule antagonist it1t in p1 spacegroup 3.1Å AUTH B.WU,E.Y.CHIEN,C.D.MOL,G.FENALTI,W.LIU,V.KATRITCH,R.ABAGYAN,AUTH 2 A.BROOUN,P.WELLS,F.C.BI,D.J.HAMEL,P.KUHN,T.M.HANDEL,AUTH 3 V.CHEREZOV,R.C.STEVENSTITL STRUCTURES OF THE CXCR4 CHEMOKINE GPCR WITH SMALL-MOLECULETITL 2 AND CYCLIC PEPTIDE ANTAGONISTS.REF SCIENCE V. 330 1066 2010REFN ISSN 0036-8075PMID 20929726DOI 10.1126/SCIENCE.1194396 Variant Set Distributions […]
General Structure Information 2e8p ELF3 solution structure of the n-terminal sam-domain of e74-like factor 3 -1.0Å AUTH A.K.GORONCY,M.SATO,S.KOSHIBA,S.WATANABE,T.HARADA,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE N-TERMINAL SAM-DOMAIN OFTITL 2 E74-LIKE FACTOR 3REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2ctj HDLBP solution structure of the 8th kh type i domain from human vigilin -1.0Å AUTH T.TOMIZAWA,T.KIGAWA,S.KOSHIBA,M.INOUE,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE 8TH KH TYPE I DOMAINTITL 2 FROM HUMAN VIGILINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants