Assessment of Structural Intolerance and Durability
General Structure Information 1nbq F11R crystal structure of human junctional adhesion molecule type 1 2.9Å AUTH A.E.PROTA,J.A.CAMPBELL,P.SCHELLING,J.C.FORREST,AUTH 2 M.J.WATSON,T.R.PETERS,M.AURRAND-LIONS,B.A.IMHOF,AUTH 3 T.S.DERMODY,T.STEHLETITL CRYSTAL STRUCTURE OF HUMAN JUNCTIONAL ADHESIONTITL 2 MOLECULE 1: IMPLICATIONS FOR REOVIRUS BINDINGREF PROC.NATL.ACAD.SCI.USA V. 100 5366 2003REFN ISSN 0027-8424PMID 12697893DOI 10.1073/PNAS.0937718100 Variant Set Distributions Mapped Variants
General Structure Information 2v9r ROBO1 first and second ig domains from human robo1 (form 2) 2.0Å AUTH C.MORLOT,N.M.THIELENS,R.B.RAVELLI,W.HEMRIKA,R.A.ROMIJN,AUTH 2 P.GROS,S.CUSACK,A.A.MCCARTHYTITL STRUCTURAL INSIGHTS INTO THE SLIT-ROBO COMPLEX.REF PROC.NAT.ACAD.SCI.USA V. 104 14923 2007REFN ISSN 0027-8424PMID 17848514DOI 10.1073/PNAS.0705310104 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3bin EPB41L3 structure of the dal-1 and tslc1 (372-383) complex 2.3Å AUTH R.D.BUSAM,A.-G.THORSELL,A.FLORES,M.HAMMARSTROM,C.PERSSON,AUTH 2 B.OBRINK,B.M.HALLBERGTITL STRUCTURAL BASIS OF TUMOR SUPPRESSOR IN LUNG CANCER 1TITL 2 (TSLC1) BINDING TO DIFFERENTIALLY EXPRESSED INTITL 3 ADENOCARCINOMA OF THE LUNG (DAL-1/4.1B)REF J.BIOL.CHEM. V. 286 4511 2011REFN ISSN 0021-9258PMID 21131357DOI 10.1074/JBC.M110.174011 Variant Set Distributions Ripley’s K Analysis […]
General Structure Information 3k0w MALT1 crystal structure of the tandem ig-like c2-type 2 domains of the human mucosa-associated lymphoid tissue lymphoma translocation protein 1 2.8Å AUTH J.R.WALKER,L.QIU,C.BUTLER-COLE,C.BOUNTRA,J.WEIGELT,AUTH 2 C.H.ARROWSMITH,A.M.EDWARDS,A.BOCHKAREV,AUTH 3 S.DHE-PAGANONTITL STRUCTURE OF THE TANDEM IG-LIKE C2-TYPE 2 DOMAINSTITL 2 OF THE HUMAN MUCOSA-ASSOCIATED LYMPHOID TISSUETITL 3 LYMPHOMA TRANSLOCATION PROTEIN 1.REF TO BE PUBLISHEDREFN Variant […]
General Structure Information 2kdg MYOT solution structure of the 1st ig domain of myotilin -1.0Å AUTH O.HEIKKINEN,P.PERMI,H.KOSKELA,O.CARPEN,J.YLANNE,AUTH 2 I.KILPELAINENTITL SOLUTION STRUCTURE OF THE FIRST IMMUNOGLOBULINTITL 2 DOMAIN OF HUMAN MYOTILINREF J.BIOMOL.NMR V. 44 107 2009REFN ISSN 0925-2738PMID 19418025DOI 10.1007/S10858-009-9320-4 Variant Set Distributions Mapped Variants
General Structure Information 2kkq MYOT solution nmr structure of the ig-like c2-type 2 domain of human myotilin. northeast structural genomics target hr3158. -1.0Å AUTH P.ROSSI,G.T.MONTELIONETITL SOLUTION NMR STRUCTURE OF THE IG-LIKE C2-TYPE 2TITL 2 DOMAIN OF HUMAN MYOTILIN. NORTHEAST STRUCTURALTITL 3 GENOMICS TARGET HR3158.REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 3fn3 CD274 dimeric structure of pd-l1 2.7Å AUTH Y.CHEN,P.LIU,F.GAO,H.CHENG,J.QI,G.F.GAOTITL A DIMERIC STRUCTURE OF PD-L1: FUNCTIONAL UNITS ORTITL 2 EVOLUTIONARY RELICS?REF PROTEIN CELL V. 1 153 2010REFN ISSN 1674-800XPMID 21203985DOI 10.1007/S13238-010-0022-1 Variant Set Distributions Mapped Variants
General Structure Information 3mqi EBF1 human early b-cell factor 1 (ebf1) ipt/tig domain 2.3Å AUTH M.I.SIPONEN,M.WISNIEWSKA,L.LEHTIO,I.JOHANSSON,L.SVENSSON,AUTH 2 G.RASZEWSKI,L.NILSSON,M.SIGVARDSSON,H.BERGLUNDTITL STRUCTURAL DETERMINATION OF FUNCTIONAL DOMAINS IN EARLYTITL 2 B-CELL FACTOR (EBF) FAMILY OF TRANSCRIPTION FACTORS REVEALSTITL 3 SIMILARITIES TO REL DNA-BINDING PROTEINS AND A NOVELTITL 4 DIMERIZATION MOTIF.REF J.BIOL.CHEM. V. 285 25875 2010REFN ISSN 0021-9258PMID 20592035DOI 10.1074/JBC.C110.150482 […]
General Structure Information 2pkd CD84 crystal structure of cd84: insite into slam family function 2.04Å AUTH Q.YAN,V.N.MALASHKEVICH,A.FEDOROV,E.FEDOROV,E.CAO,AUTH 2 J.W.LARY,J.L.COLE,S.G.NATHENSON,S.C.ALMOTITL STRUCTURE OF CD84 PROVIDES INSIGHT INTO SLAMTITL 2 FAMILY FUNCTION.REF PROC.NATL.ACAD.SCI.USA V. 104 10583 2007REFN ISSN 0027-8424PMID 17563375DOI 10.1073/PNAS.0703893104 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 2q87 CD300A the crystal structure of the human irp60 ectodomain 1.7Å AUTH N.DIMASI,J.A.MARQUEZTITL THE CRYSTAL STRUCTURE OF IRP60 ECTODOMAINREF TO BE PUBLISHED 2007REFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants