General Structure Information 3jw0 NEDD4L e2~ubiquitin-hect 3.1Å AUTH H.B.KAMADURAI,J.SOUPHRON,D.C.SCOTT,D.M.DUDA,D.J.MILLER,AUTH 2 D.STRINGER,R.C.PIPER,B.A.SCHULMANTITL INSIGHTS INTO UBIQUITIN TRANSFER CASCADES FROM A STRUCTURETITL 2 OF A UBCH5B APPROXIMATELY UBIQUITIN-HECT(NEDD4L) COMPLEX.REF MOL.CELL V. 36 1095 2009REFN ISSN 1097-2765PMID 20064473DOI 10.1016/J.MOLCEL.2009.11.010 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 3gcw PCSK9 pcsk9:egfa(h306y) 2.7Å AUTH M.C.MCNUTT,H.J.KWON,C.CHEN,J.R.CHEN,J.D.HORTON,T.A.LAGACETITL ANTAGONISM OF SECRETED PCSK9 INCREASES LOW DENSITYTITL 2 LIPOPROTEIN RECEPTOR EXPRESSION IN HEPG2 CELLS.REF J.BIOL.CHEM. V. 284 10561 2009REFN ISSN 0021-9258PMID 19224862DOI 10.1074/JBC.M808802200 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 3gcx PCSK9 pcsk9:egfa (ph 7.4) 2.7Å AUTH M.C.MCNUTT,H.J.KWON,C.CHEN,J.R.CHEN,J.D.HORTON,T.A.LAGACETITL ANTAGONISM OF SECRETED PCSK9 INCREASES LOW DENSITYTITL 2 LIPOPROTEIN RECEPTOR EXPRESSION IN HEPG2 CELLS.REF J.BIOL.CHEM. V. 284 10561 2009REFN ISSN 0021-9258PMID 19224862DOI 10.1074/JBC.M808802200 Variant Set Distributions Mapped Variants
General Structure Information 3be2 KDR crystal structure of the vegfr2 kinase domain in complex with a benzamide inhibitor 1.75Å AUTH J.C.HARMANGE,M.M.WEISS,J.GERMAIN,A.J.POLVERINO,AUTH 2 G.BORG,J.BREADY,D.CHEN,D.CHOQUETTE,A.COXON,AUTH 3 T.DEMELFI,L.DIPIETRO,N.DOERR,J.ESTRADA,J.FLYNN,AUTH 4 R.F.GRACEFFA,S.P.HARRIMAN,S.KAUFMAN,D.S.LA,A.LONG,AUTH 5 M.W.MARTIN,S.NEERVANNAN,V.F.PATEL,M.POTASHMAN,AUTH 6 K.REGAL,P.M.ROVETO,M.L.SCHRAG,C.STARNES,A.TASKER,AUTH 7 Y.TEFFERA,L.WANG,R.D.WHITE,D.A.WHITTINGTON,R.ZANONTITL NAPHTHAMIDES AS NOVEL AND POTENT VASCULARTITL 2 ENDOTHELIAL GROWTH FACTOR RECEPTOR TYROSINE KINASETITL 3 INHIBITORS: DESIGN, SYNTHESIS, AND EVALUATION.REF J.MED.CHEM. V. 51 […]