Assessment of Structural Intolerance and Durability
General Structure Information 1yk0 NPR3 structure of natriuretic peptide receptor-c complexed with atrial natriuretic peptide 2.4Å AUTH X.L.HE,A.DUKKIPATI,K.C.GARCIATITL STRUCTURAL DETERMINANTS OF NATRIURETIC PEPTIDE RECEPTORTITL 2 SPECIFICITY AND DEGENERACY.REF J.MOL.BIOL. V. 361 698 2006REFN ISSN 0022-2836PMID 16870210DOI 10.1016/J.JMB.2006.06.060 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Mapped Variants
General Structure Information 1nq0 THRB tr receptor mutations conferring hormone resistance and reduced corepressor release exhibit decreased stability in the nterminal lbd 2.4Å AUTH B.R.HUBER,M.DESCLOZEAUX,B.L.WEST,S.T.CUNHA-LIMA,H.T.NGUYEN,AUTH 2 J.D.BAXTER,H.A.INGRAHAM,R.J.FLETTERICKTITL THYROID HORMONE RECEPTOR-BETA MUTATIONS CONFERRING HORMONETITL 2 RESISTANCE AND REDUCED COREPRESSOR RELEASE EXHIBIT DECREASEDTITL 3 STABILITY IN THE N-TERMINAL LIGAND-BINDING DOMAINREF MOL.ENDOCRINOL. V. 17 107 2003REFN ISSN 0888-8809PMID […]