General Structure Information
| PDB ID | 1yk0 |
| HGNC Gene Label(s) | NPR3 |
| Structure Name | structure of natriuretic peptide receptor-c complexed with atrial natriuretic peptide |
| Resolution | 2.4Å |
| Reference | AUTH X.L.HE,A.DUKKIPATI,K.C.GARCIATITL STRUCTURAL DETERMINANTS OF NATRIURETIC PEPTIDE RECEPTORTITL 2 SPECIFICITY AND DEGENERACY.REF J.MOL.BIOL. V. 361 698 2006REFN ISSN 0022-2836PMID 16870210DOI 10.1016/J.JMB.2006.06.060 |
Variant Set Distributions
ExAC Variants
| Number Of Residues | 394 |
| Number Of SNVs | 89 |
| Number Of Permutations | 48969 |
| Optimal Distance Threshold | 13.0 |
| K Statistic | 0.085 |
| p-value | 0.173 |
COSMIC
| Number Of Residues | 394 |
| Number Of SNVs | 4 |
| Number Of Permutations | 16 |
| Optimal Distance Threshold | 16.0 |
| K Statistic | 0.333 |
| p-value | 0.423 |
Ripley’s K Analysis Plots
ExACCOSMIC
Variant Set Comparisons
Cosmic vs. ExAC
| Number Of ExAC SNVs | 89 |
| Number Of COSMIC SNVs | 5 |
| Optimal Distance Threshold | 26.0 |
| K Statistic | 0.485 |
| p-value | 0.078 |