General Structure Information 4bzc SAMHD1 crystal structure of the tetrameric dgtp-bound wild type samhd1 catalytic core 2.88Å AUTH X.JI,Y.WU,J.YAN,J.MEHRENS,H.YANG,M.DELUCIA,C.HAO,AUTH 2 A.M.GRONENBORN,J.SKOWRONSKI,J.AHN,Y.XIONGTITL MECHANISM OF ALLOSTERIC ACTIVATION OF SAMHD1 BY DGTPREF NAT.STRUCT.MOL.BIOL. V. 20 1304 2013REFN ISSN 1545-9993PMID 24141705DOI 10.1038/NSMB.2692 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants
General Structure Information 4cc9 VPRBP crystal structure of human samhd1 (amino acid residues 582- 626) bound to vpx isolated from sooty mangabey and human dcaf1 (amino acid residues 1058-1396) 2.47Å AUTH D.SCHWEFEL,H.C.T.GROOM,V.C.BOUCHERIT,E.CHRISTODOULOU,AUTH 2 P.A.WALKER,J.P.STOYE,K.N.BISHOP,I.A.TAYLORTITL STRUCTURAL BASIS OF LENTIVIRAL SUBVERSION OF A CELLULARTITL 2 PROTEIN DEGRADATION PATHWAY.REF NATURE V. 505 234 2014REFN ISSN 0028-0836PMID 24336198DOI 10.1038/NATURE12815 […]
General Structure Information 3vow APOBEC3C crystal structure of the human apobec3c having hiv-1 vif-binding interface 2.15Å AUTH S.KITAMURA,H.ODE,M.NAKASHIMA,M.IMAHASHI,Y.NAGANAWA,AUTH 2 T.KUROSAWA,Y.YOKOMAKU,T.YAMANE,N.WATANABE,A.SUZUKI,AUTH 3 W.SUGIURA,Y.IWATANITITL THE APOBEC3C CRYSTAL STRUCTURE AND THE INTERFACE FOR HIV-1TITL 2 VIF BINDING.REF NAT.STRUCT.MOL.BIOL. V. 19 1005 2012REFN ISSN 1545-9993PMID 23001005DOI 10.1038/NSMB.2378 Variant Set Distributions Mapped Variants
General Structure Information 2olm AGFG1 arfgap domain of hiv-1 rev binding protein 1.48Å AUTH Y.TONG,W.TEMPEL,L.SHEN,S.DIMOV,R.LANDRY,C.H.ARROWSMITH,AUTH 2 A.M.EDWARDS,M.SUNDSTROM,J.WEIGELT,A.BOCHKAREV,H.PARK,AUTH 3 STRUCTURAL GENOMICS CONSORTIUM (SGC)TITL ARFGAP DOMAIN OF HIV-1 REV BINDING PROTEINREF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants
General Structure Information 2lsp BRD4 solution structures of brd4 second bromodomain with nf-kb-k310ac peptide -1.0Å AUTH G.ZHANG,R.LIU,Y.ZHONG,A.N.PLOTNIKOV,W.ZHANG,L.ZENG,AUTH 2 E.RUSINOVA,G.GERONA-NEVARRO,N.MOSHKINA,J.JOSHUA,P.Y.CHUANG,AUTH 3 M.OHLMEYER,J.C.HE,M.M.ZHOUTITL DOWN-REGULATION OF NF-KAPPA B TRANSCRIPTIONAL ACTIVITY INTITL 2 HIV-ASSOCIATED KIDNEY DISEASE BY BRD4 INHIBITION.REF J.BIOL.CHEM. V. 287 28840 2012REFN ISSN 0021-9258PMID 22645123DOI 10.1074/JBC.M112.359505 Variant Set Distributions Mapped Variants