4CC9.A | VPRBP

General Structure Information

PDB ID 4cc9
HGNC Gene Label(s) VPRBP
Structure Name crystal structure of human samhd1 (amino acid residues 582- 626) bound to vpx isolated from sooty mangabey and human dcaf1 (amino acid residues 1058-1396)
Resolution 2.47Å
Reference AUTH D.SCHWEFEL,H.C.T.GROOM,V.C.BOUCHERIT,E.CHRISTODOULOU,AUTH 2 P.A.WALKER,J.P.STOYE,K.N.BISHOP,I.A.TAYLORTITL STRUCTURAL BASIS OF LENTIVIRAL SUBVERSION OF A CELLULARTITL 2 PROTEIN DEGRADATION PATHWAY.REF NATURE V. 505 234 2014REFN ISSN 0028-0836PMID 24336198DOI 10.1038/NATURE12815

Variant Set Distributions

ExAC Variants

Number Of Residues 307
Number Of SNVs 34
Number Of Permutations 11953
Optimal Distance Threshold 6.0
K Statistic 0.021
p-value 0.726

Mapped Variants

[+] ExAC Missense Variants