2DMP.A | ZHX2

General Structure Information 2dmp ZHX2 solution structure of the third homeobox domain of zinc fingers and homeoboxes protein 2 -1.0Å AUTH S.OHNISHI,A.SASAGAWA,K.SAITO,S.KOSHIBA,M.INOUE,AUTH 2 T.KIGAWA,S.YOKOYAMATITL SOLUTION STRUCTURE OF THE THIRD HOMEOBOX DOMAIN OFTITL 2 ZINC FINGERS AND HOMEOBOXES PROTEIN 2REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants

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2DMQ.A | LHX9

General Structure Information 2dmq LHX9 solution structure of the homeobox domain of lim/homeobox protein lhx9 -1.0Å AUTH S.OHNISHI,N.TOCHIO,S.KOSHIBA,M.INOUE,T.KIGAWA,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE HOMEOBOX DOMAIN OFTITL 2 LIM/HOMEOBOX PROTEIN LHX9REF TO BE PUBLISHEDREFN Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants

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2DA4.A | HDX

General Structure Information 2da4 HDX solution structure of the homeobox domain of the hypothetical protein, dkfzp686k21156 -1.0Å AUTH S.OHNISHI,T.KIGAWA,K.SAITO,S.KOSHIBA,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE HOMEOBOX DOMAIN OF THETITL 2 HYPOTHETICAL PROTEIN, DKFZP686K21156REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants

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2DA2.A | ZFHX3

General Structure Information 2da2 ZFHX3 solution structure of the second homeobox domain of at- binding transcription factor 1 (atbf1) -1.0Å AUTH S.OHNISHI,T.KIGAWA,N.TOCHIO,S.KOSHIBA,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE SECOND HOMEOBOX DOMAINTITL 2 OF AT-BINDING TRANSCRIPTION FACTOR 1 (ATBF1)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants

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2DA1.A | ZFHX3

General Structure Information 2da1 ZFHX3 solution structure of the first homeobox domain of at- binding transcription factor 1 (atbf1) -1.0Å AUTH S.OHNISHI,T.KIGAWA,T.TOMIZAWA,S.KOSHIBA,M.INOUE,AUTH 2 S.YOKOYAMATITL SOLUTION STRUCTURE OF THE FIRST HOMEOBOX DOMAIN OFTITL 2 AT-BINDING TRANSCRIPTION FACTOR 1 (ATBF1)REF TO BE PUBLISHEDREFN Variant Set Distributions Mapped Variants

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4O9B.A | STIM1

General Structure Information 4o9b STIM1 the structure of cc1-ih in human stim1. 2.6Å AUTH B.CUI,X.YANG,S.LI,Z.LIN,Z.WANG,C.DONG,Y.SHENTITL THE INHIBITORY HELIX CONTROLS THE INTRAMOLECULARTITL 2 CONFORMATIONAL SWITCHING OF THE C-TERMINUS OF STIM1.REF PLOS ONE V. 8 74735 2013REFN ESSN 1932-6203PMID 24069340DOI 10.1371/JOURNAL.PONE.0074735 Variant Set Distributions Mapped Variants

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3H7H.A | SUPT4H1

General Structure Information 3h7h SUPT4H1 crystal structure of the human transcription elongation factor dsif, hspt4/hspt5 (176-273) 1.55Å AUTH S.WENZEL,B.M.MARTINS,P.ROSCH,B.M.WOHRLTITL CRYSTAL STRUCTURE OF THE HUMAN TRANSCRIPTION ELONGATIONTITL 2 FACTOR DSIF HSPT4 SUBUNIT IN COMPLEX WITH THE HSPT5TITL 3 DIMERIZATION INTERFACEREF BIOCHEM.J. V. 425 373 2010REFN ISSN 0264-6021PMID 19860741DOI 10.1042/BJ20091422 Variant Set Distributions Mapped Variants

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3H7H.A | SUPT4H1

General Structure Information 3h7h SUPT4H1 crystal structure of the human transcription elongation factor dsif, hspt4/hspt5 (176-273) 1.55Å AUTH S.WENZEL,B.M.MARTINS,P.ROSCH,B.M.WOHRLTITL CRYSTAL STRUCTURE OF THE HUMAN TRANSCRIPTION ELONGATIONTITL 2 FACTOR DSIF HSPT4 SUBUNIT IN COMPLEX WITH THE HSPT5TITL 3 DIMERIZATION INTERFACEREF BIOCHEM.J. V. 425 373 2010REFN ISSN 0264-6021PMID 19860741DOI 10.1042/BJ20091422 Variant Set Distributions Mapped Variants

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4MBS.B | CCR5

General Structure Information 4mbs CCR5 crystal structure of the ccr5 chemokine receptor 2.71Å AUTH Q.TAN,Y.ZHU,J.LI,Z.CHEN,G.W.HAN,I.KUFAREVA,T.LI,L.MA,AUTH 2 G.FENALTI,J.LI,W.ZHANG,X.XIE,H.YANG,H.JIANG,V.CHEREZOV,AUTH 3 H.LIU,R.C.STEVENS,Q.ZHAO,B.WUTITL STRUCTURE OF THE CCR5 CHEMOKINE RECEPTOR-HIV ENTRY INHIBITORTITL 2 MARAVIROC COMPLEX.REF SCIENCE V. 341 1387 2013REFN ISSN 0036-8075PMID 24030490DOI 10.1126/SCIENCE.1241475 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants

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2AEX.A | CPOX

General Structure Information 2aex CPOX the 1.58a crystal structure of human coproporphyrinogen oxidase reveals the structural basis of hereditary coproporphyria 1.58Å AUTH D.S.LEE,E.FLACHSOVA,M.BODNAROVA,B.DEMELER,P.MARTASEK,AUTH 2 C.S.RAMANTITL STRUCTURAL BASIS OF HEREDITARY COPROPORPHYRIA.REF PROC.NATL.ACAD.SCI.USA V. 102 14232 2005REFN ISSN 0027-8424PMID 16176984DOI 10.1073/PNAS.0506557102 Variant Set Distributions Ripley’s K Analysis Plots Variant Set Comparisons Pathogenic Proximity Analysis Mapped Variants

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